Asset profile

JS207

Multispecific antibody

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

61 competitors in this universe: 1 direct rival (same mechanism and indication), 0 same-class, 60 same-indication; 61 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
JS207: this drugPhase 2Multispecific antibodyPD-1 + VEGFA
IvonescimabPhase 3Multispecific antibodyPD-1 + VEGFA
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET
AtezolizumabApprovedMonoclonal antibodyPD-L1
BAT1706 (Avzivi)ApprovedMonoclonal antibodyVEGF-A
BAY2927088 (Hyrnuo)ApprovedSmall moleculeHER2 (ERBB2) exon 20 insertions and point mutations; also mutant-selective EGFR
BevacizumabApprovedMonoclonal antibodyVEGF-A, Vascular Endothelial Growth Factor Inhibitor
Bevacizumab-Awwb (MVASI)ApprovedMonoclonal antibodyVEGF-A
BinimetinibApprovedSmall moleculeMEK1/2
BrigatinibApprovedSmall moleculeALK
CapmatinibApprovedSmall moleculeMET
CemiplimabApprovedMonoclonal antibodyPD-1
CeritinibApprovedSmall moleculeALK

…and 46 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(13 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
November 2026 (1)
Phase 2Advanced Colorectal CancerRecruiting
Est. primary completion 2026-11-27 · NCT06885385 · CT.gov ↗
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December 2026 (1)
Phase 1Advanced Malignant Solid TumorsActive not recruiting
Est. primary completion 2026-12-15 · NCT06571422 · CT.gov ↗
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2027 (9)
April 2027 (1)
Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-04-30 · NCT06944470 · CT.gov ↗
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November 2027 (2)
Phase 2Advanced Malignant Solid TumorsRecruiting
Est. primary completion 2027-11-30 · NCT07480733 · CT.gov ↗
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Phase 2Advanced Lung CancerRecruiting
Est. primary completion 2027-11-30 · NCT07309276 · CT.gov ↗
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December 2027 (6)
Phase 2Metastatic Colorectal CancerRecruiting
Est. primary completion 2027-12-30 · NCT07503756 · CT.gov ↗
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Phase 1/2Solid TumorRecruiting
Est. primary completion 2027-12-31 · NCT07466160 · CT.gov ↗
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Phase 2Breast Neoplasm, Breast Cancer, Breast Tumors, Triple-Negative Breast Cancer (TNBC), HER2-positive Breast Cancer …Recruiting
Est. primary completion 2027-12-31 · NCT05582499 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-12-31 · NCT06969027 · CT.gov ↗
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Phase 2Hepatocellular CarcinomaRecruiting
Est. primary completion 2027-12-31 · NCT06954467 · CT.gov ↗
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Phase 2Recurrent/ Metastatic NPCRecruiting
Est. primary completion 2027-12-31 · NCT07690787 · CT.gov ↗
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2028 (1)
March 2028 (1)
Phase 2Triple-negative Breast CancerRecruiting
Est. primary completion 2028-03-22 · NCT07045311 · CT.gov ↗
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2029 (1)
June 2029 (1)
Phase 1/2Advanced Solid TumorRecruiting
Est. primary completion 2029-06-30 · NCT06953323 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (12)
Phase 1/2 (2)
Phase 1 (2)