Asset profile
AZD4604
Unknown / undisclosed
Evidence outlook · results not reported
AJAX (NCT06020014) · Asthma
The lead study's design has limits that temper confidence (see the rationale below), and its results have not been reported. This tier describes the design, not an outcome.
AJAX (NCT06020014): The study was randomized, quadruple-blind, and placebo-controlled, with 339 participants enrolled. Its primary endpoint was time to the first CompEx Asthma event, a composite surrogate measure, and results are not posted, so whether the primary comparison was met or missed is unknown.
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Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
70 competitors in this universe: 1 direct rival (same mechanism and indication), 9 same-class, 60 same-indication; 66 further along in development.
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| AZD4604: this drug | Phase 2 | — | JAK1 | ||
| AZD0449 | Phase 1 | — | JAK1 | ||
| Abrocitinib (Cibinqo) | Approved | Small molecule | JAK1 | ||
| Upadacitinib (Rinvoq) | Approved | Small molecule | JAK, JAK1 | ||
| Filgotinib (Jyseleca) | Phase 3 | Small molecule | JAK, JAK1 | ||
| LNK01001 | Phase 3 | Small molecule | JAK1 | ||
| LW402 | Phase 3 | Small molecule | JAK1 | ||
| VC005 | Phase 3 | Small molecule | JAK1, JAK1 | ||
| GSK2586184 | Phase 2 | Small molecule | JAK1, JAK1 | ||
| IN-115314 | Phase 2 | Small molecule | JAK1 | ||
| JYP0061 | Phase 2 | Small molecule | JAK1 | ||
| Albuterol (Armstrong Albuterol HFA) | Approved | Small molecule | Beta-2 adrenergic receptor | ||
| Albuterol / Budesonide (Airsupra) | Approved | Combination | Beta-2 adrenergic receptor, Glucocorticoid receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor | ||
| Albuterol HFA (Armstrong's) | Approved | Small molecule | Beta-2 adrenergic receptor | ||
| Albuterol HFA (Proventil HFA) | Approved | Small molecule | Beta-2 adrenergic receptor | ||
| Albuterol Sulfate (Armstrong) | Approved | Small molecule | Beta-2 adrenergic receptor |
…and 55 more. Research shows the complete landscape.
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Upcoming events
No upcoming readouts on record for this asset.
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.