Headquarters
USA
Every company in the roster headquartered in USA.
Research
Compare company financial metrics
Research adds sourced market cap, cash, runway and annualized R&D figures with metric-specific sorting.
Headquarters
Every company in the roster headquartered in USA.
Research adds sourced market cap, cash, runway and annualized R&D figures with metric-specific sorting.
165 of 165 companies
| Company | Pipeline | Most advanced | Next readout |
|---|---|---|---|
Halia TherapeuticsPrivate | 1 asset: 1 Ph 2 | HT-4253Phase 2 · Alzheimer's Disease | Feb 2028HT-4253 · Phase 2 |
HeartWorksPrivate | 1 asset: 1 Ph 1 | iPSC-CLPhase 1 · Heart Failure | Sep 2027iPSC-CL · Phase 1 |
Humanetics CorporationPrivate | 1 asset: 1 Ph 2 | BIO 300Phase 2 · Non-Small Cell Lung CancerWeak signal | None on record |
INmune BioINMB · Nasdaq | 1 asset: 1 Ph 2 | XPro1595Phase 2 · Alzheimer's DiseasePartial signal | None on record |
Imbria PharmaceuticalsPrivate | 1 asset: 1 Ph 2 | NinerafaxstatPhase 2 · Heart FailureWeak signal | Dec 2026Ninerafaxstat · Phase 2 |
IntralytixPrivate | 1 asset: 1 Ph 2 | EcoActivePhase 1/2 · Crohn's Disease | None on record |
Jasper Therapeutics, Inc.JSPR · Nasdaq | 1 asset: 1 Ph 2 | BriquilimabPhase 2 · AsthmaPartial signal | None on record |
Jina PharmaceuticalsPrivate | 1 asset: 1 Ph 2 | nanosomal tacrolimusPhase 2 · Ulcerative Colitis | None on record |
KallyopePrivate | 1 asset: 1 Ph 3 | ElismetrepPhase 3 · Migraine | Feb 2027Elismetrep · Phase 3 |
Kestrel TherapeuticsPrivate | 1 asset: 1 Ph 1 | KST-6051Phase 1 · Non-Small Cell Lung Cancer | Jun 2027KST-6051 · Phase 1 |
Kinaset TherapeuticsPrivate | 1 asset: 1 Ph 2 | frevecitinibPhase 2 · Chronic Obstructive Pulmonary DiseasePartial signal | 30 Nov 2027frevecitinib · Phase 2 |
LAPIX TherapeuticsPrivate | 1 asset: 1 Ph 1 | LPX-TI641Phase 1 · Psoriatic Arthritis | None on record |
Lexeo TherapeuticsLXEO · Nasdaq | 1 asset: 1 Ph 2 | LX1001Phase 1/2 · Alzheimer's DiseaseWeak signal | Nov 2028LX1001 · Phase 1 |
Libella Gene TherapeuticsPrivate | 1 asset: 1 Ph 1 | AAV-hTERTPhase 1 · Alzheimer's DiseaseWeak signal | None on record |
Lighthouse PharmaceuticalsPrivate | 1 asset: 1 Ph 2 | LHP588Phase 2 · Alzheimer's Disease | 31 Jan 2029LHP588 · Phase 2 |
Lisata TherapeuticsLSTA · Nasdaq | 1 asset: 1 Ph 2 | certepetidePhase 2 · Pancreatic Cancer | None on record |
Longeveron (NASDAQ: LGVN)LGVN · Nasdaq | 1 asset: 1 Ph 2 | LaromestrocelPhase 2 · Alzheimer's DiseasePartial signal | None on record |
MTI Biotech Inc.Private | 1 asset: 1 Ph 2 | 2-hydroxybenzylamine acetatePhase 1/2 · Alzheimer's Disease | 30 Dec 20282-hydroxybenzylamine acetate · Phase 1/2 |
MapLight TherapeuticsMPLT · Nasdaq | 1 asset: 1 Ph 2 | ML-007C-MAPhase 2 · SchizophreniaPartial signal | Dec 2027ML-007C-MA · Phase 2 |
Mineralys TherapeuticsMLYS · Nasdaq | 1 asset: 1 Ph 3 | LorundrostatPhase 3 · HypertensionReliable signal | None on record |
NGM BiopharmaceuticalsPrivate | 1 asset: 1 Ph 2 | NGM707Phase 1/2 · Non-Small Cell Lung CancerWeak signal | None on record |
NKGen BiotechNKGN · OTC | 1 asset: 1 Ph 2 | SNK01Phase 1/2 · Alzheimer's DiseaseWeak signal | Mar 2028SNK01 · Phase 1/2 |
NSC-TherapeuticsPrivate | 1 asset: 1 Ph 2 | NSC001Phase 1/2 · Alzheimer's Disease | None on record |
| 1 asset: 1 Ph 2 | TraneurocinPhase 2 · Alzheimer's DiseasePartial signal | None on record | |
NeuroPro Therapeutics, Inc.Private | 1 asset: 1 Ph 2 | NPT2042Phase 2 · EpilepsyPartial signal | None on record |
NeuroTherapia, Inc.Private | 1 asset: 1 Ph 2 | NTRX-07Phase 2 · Alzheimer's DiseasePartial signal | None on record |
Neuronascent, Inc.Private | 1 asset: 1 Ph 1 | NNI-362Phase 1 · Alzheimer's DiseasePartial signal | None on record |
Odyssey TherapeuticsPrivate | 1 asset: 1 Ph 2 | OD-07656Phase 2 · Ulcerative ColitisWeak signal | None on record |
Oligomerix, IncPrivate | 1 asset: 1 Ph 1 | OLX-07010Phase 1 · Alzheimer's Disease | None on record |
Palisade BioPALI · Nasdaq | 1 asset: 1 Ph 2 | PALI-2108Phase 2 · Ulcerative ColitisPartial signal | Oct 2027PALI-2108 · Phase 2 |
PharmatrophiXPrivate | 1 asset: 1 Ph 2 | LM11A-31Phase 1/2 · Alzheimer's DiseasePartial signal | None on record |
PulmatrixPULM · Nasdaq | 1 asset: 1 Ph 2 | PUR1900Phase 2 · Allergic Bronchopulmonary Aspergillosis | None on record |
PulmovantPrivate | 1 asset: 1 Ph 3 | MosliciguatPhase 3 · Pulmonary Hypertension | Dec 2026Mosliciguat · Phase 2 |
Quince TherapeuticsQNCX · Nasdaq | 1 asset: 1 Ph 2 | LAM-001Phase 2 · Bronchiolitis Obliterans Syndrome | Mar 2028LAM-001 · Phase 2 |
ReAlta Life SciencesPrivate | 1 asset: 1 Ph 2 | RLS-0071Phase 2 · Chronic Obstructive Pulmonary Disease | Dec 2026RLS-0071 · Phase 2 |
| 1 asset: 1 Ph 2 | RB-ADSCPhase 2 · Alzheimer's Disease | Sep 2028RB-ADSC · Phase 1 | |
Retension PharmaceuticalsPrivate | 1 asset: 1 Ph 2 | RTN-001Phase 2 · Hypertension | Mar 2027RTN-001 · Phase 2 |
Rise TherapeuticsPrivate | 1 asset: 1 Ph 1 | R-3750Phase 1 · Ulcerative Colitis | 30 Apr 2028R-3750 · Phase 1 |
River 2 RenalPrivate | 1 asset: 1 Ph 2 | R2R01Phase 2 · Heart FailurePartial signal | 1 Apr 2027R2R01 · Phase 2 |
Rivus PharmaceuticalsPrivate | 1 asset: 1 Ph 2 | HU6Phase 2 · Heart FailurePartial signal | Feb 2027HU6 · Phase 2 |
Sagimet Biosciences Inc.SGMT · Nasdaq | 1 asset: 1 Ph 3 | DenifanstatPhase 3 · MASH / NASHReliable signal | None on record |
Sardocor (Medera Biopharma)Private | 1 asset: 1 Ph 2 | AAV1.SERCA2aPhase 1/2 · Heart Failure | Oct 2027AAV1.SERCA2a · Phase 1 |
Sarfez PharmaceuticalsPrivate | 1 asset: 1 approved | Approved assets only | None on record |
SatRxPrivate | 1 asset: 1 Ph 3 | GosogliptinPhase 3 · Type 2 DiabetesPartial signal | None on record |
Scholar RockSRRK · Nasdaq | 1 asset: 1 Ph 3 | apitegromabPhase 3 · Spinal Muscular AtrophyPartial signal | 1 Nov 2026apitegromab · Phase 3 |
Scilex BioPrivate | 1 asset: 1 Ph 2 | KDS2010Phase 2 · Alzheimer's Disease | 31 Jan 2027KDS2010 · Phase 2 |
Secretome TherapeuticsPrivate | 1 asset: 1 Ph 1 | STM01Phase 1 · Heart Failure | None on record |
Seismic TherapeuticPrivate | 1 asset: 1 Ph 1 | S-4321Phase 1 · Psoriatic Arthritis | Sep 2027S-4321 · Phase 1 |
Skye BioscienceSKYE · Nasdaq | 1 asset: 1 Ph 2 | nimacimabPhase 2 · Obesity | 20 Nov 2026nimacimab · Phase 2 |
Sorriso PharmaceuticalsPrivate | 1 asset: 1 Ph 1 | SOR102Phase 1 · Ulcerative ColitisPartial signal | None on record |
Sparrow PharmaceuticalsPrivate | 1 asset: 1 Ph 2 | clofutribenPhase 2 · Type 2 DiabetesWeak signal | 31 Dec 2027clofutriben · Phase 2 |
SpinogenixPrivate | 1 asset: 1 Ph 2 | SPG302Phase 2 · Alzheimer's Disease | 31 Dec 2027SPG302 · Phase 2/3 |
Structure TherapeuticsGPCR · Nasdaq | 1 asset: 1 Ph 3 | aleniglipronPhase 3 · ObesityPartial signal | Sep 2028aleniglipron · Phase 3 |
T3D TherapeuticsPrivate | 1 asset: 1 Ph 3 | T3D-959Phase 2/3 · Alzheimer's DiseasePartial signal | Apr 2031T3D-959 · Phase 2/3 |
Tectonic TherapeuticTECX · Nasdaq | 1 asset: 1 Ph 2 | Fc-relaxin fusion protein (TX45)Phase 2 · Hypertension | 24 Nov 2026Fc-relaxin fusion protein (TX45) · Phase 2 |
Tenax TherapeuticsTENX · Nasdaq | 1 asset: 1 Ph 3 | LevosimendanPhase 3 · Heart FailurePartial signal | 30 Jun 2028Levosimendan · Phase 3 |
Therini Bio, Inc.Private | 1 asset: 1 Ph 1 | THN391Phase 1 · Alzheimer's Disease | 31 Mar 2027THN391 · Phase 1 |
Upstream BioUPB · Nasdaq | 1 asset: 1 Ph 2 | verekitugPhase 2 · Chronic Obstructive Pulmonary DiseaseReliable signal | Sep 2027verekitug · Phase 2 |
Vaccinex, Inc.VCNX · OTC | 1 asset: 1 Ph 2 | PepinemabPhase 1/2 · Alzheimer's DiseasePartial signal | 31 Dec 2028Pepinemab · Phase 1/2 |
Vantive HealthPrivate | 1 asset: 1 approved | Approved assets only | None on record |
Vasa TherapeuticsPrivate | 1 asset: 1 Ph 1 | Vasa Therapeutics VS-041Phase 1 · Heart Failure | None on record |
VentrixPrivate | 1 asset: 1 Ph 1 | VentriGelPhase 1 · Heart FailureWeak signal | None on record |
Virogenics, Inc.Private | 1 asset: 1 Ph 1 | CMS121Phase 1 · Alzheimer's DiseasePartial signal | None on record |
Zomagen BiosciencesPrivate | 1 asset: 1 Ph 2 | VTX3232Phase 2 · ObesityPartial signal | None on record |
scPharmaceuticalsPrivate | 1 asset: 1 approved | Approved assets only | None on record |
Next readout: the earliest estimated primary completion of a trial the company or a partner on the asset runs (ClinicalTrials.gov).