Asset profile

clofutriben

Small molecule

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

61 competitors in this universe: 0 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication; 61 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Clofutriben: this drugPhase 2Small molecule11-beta-HSD1
Emestedastat (Xanamem)Phase 2/3Small molecule11-beta-HSD1
AfrezzaApprovedPeptideInsulin receptor (basal), Insulin
Alogliptin (Nesina)ApprovedSmall moleculeDPP-4
Bexagliflozin (Brenzavvy)ApprovedSmall moleculeSGLT2
Canagliflozin (Invokana)ApprovedSmall moleculeSGLT2
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Dulaglutide (Trulicity)ApprovedPeptideGLP-1 receptor
Empagliflozin (Jardiance)ApprovedSmall moleculeSGLT2
Ertugliflozin (Steglatro)ApprovedSmall moleculeSGLT2
Glipizide (Glucotrol)ApprovedSmall moleculeSulfonylurea receptor (SUR1)
Glyburide (Diabeta / Micronase)ApprovedSmall moleculeSulfonylurea receptor (SUR1)
Insulin Aspart (NovoLog / Fiasp)ApprovedPeptideInsulin receptor
Insulin Degludec (Tresiba)ApprovedPeptideInsulin receptor (basal)
Insulin Detemir (Levemir)ApprovedPeptideInsulin receptor (basal)
Insulin Glargine (Lantus / Toujeo)ApprovedPeptideInsulin receptor (basal)

…and 46 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
December 2027 (1)
Phase 2Type 2 DiabetesRecruiting
Est. primary completion 2027-12-31 · NCT07296484 · CT.gov ↗
What to watch
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (4)
Phase 1 (4)