Asset profile

KDS2010

Small molecule

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

63 competitors in this universe: 0 direct rivals (same mechanism and indication), 3 same-class, 60 same-indication; 33 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
KDS2010: this drugPhase 2Small moleculeMAO-B
Rasagiline (Azilect)ApprovedSmall moleculeMAO-B
Safinamide (Xadago)ApprovedSmall moleculeMAO-B
HNC364Phase 1Small moleculeMAO-B
Benzgalantamine (Zunveyl)ApprovedSmall moleculeAcetylcholinesterase/nicotinic receptor (prodrug)
Brexpiprazole (Rexulti)ApprovedSmall moleculeDopamine D2/D3 and serotonin 5-HT1A receptor
Dextromethorphan / Bupropion (Auvelity)ApprovedSmall moleculesigma-1/NMDA
Donanemab (Kisunla)ApprovedMonoclonal antibodyAmyloid-beta (monoclonal antibody)
Lecanemab (Leqembi)ApprovedMonoclonal antibodyAmyloid-beta (monoclonal antibody)
Xanomeline / Trospium Chloride (Cobenfy)ApprovedSmall moleculeMuscarinic M1/M4 receptor (agonist/antagonist combination)
ACP-204Phase 3Small moleculeSerotonin 5-HT2A receptor (antagonist / inverse agonist)
AR1001Phase 3Small moleculePDE5
BezisterimPhase 3Small moleculeERK/NF-kB inflammatory
BlarcamesinePhase 3Small moleculeSigma-1 receptor / muscarinic receptor (dual)
BuntanetapPhase 3Small moleculeAPP/tau/alpha-synuclein/TDP-43 (translation)
CerebrolysinPhase 3PeptideMulti-target (ginsenoside)

…and 48 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
January 2027 (1)
Phase 2Overweight, Obesity, Obese PatientsRecruiting
Est. primary completion 2027-01-31 · NCT07009171 · CT.gov ↗
What to watch
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June 2027 (1)
Phase 2Alzheimer's DiseaseRecruiting
Est. primary completion 2027-06-30 · NCT07027072 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (2)