Asset profile

Rasagiline (Azilect)

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Parkinson's Disease

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Competitive landscape

63 competitors in this universe: 2 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Rasagiline (Azilect): this drugApprovedSmall moleculeMAO-B
Safinamide (Xadago)ApprovedSmall moleculeMAO-B
HNC364Phase 1Small moleculeMAO-B
KDS2010Phase 2Small moleculeMAO-B
Amantadine ER (Gocovri / ADS-5102)ApprovedSmall moleculeNMDA receptor
Apomorphine (Apokyn)ApprovedSmall moleculedopamine
Apomorphine Sublingual Film (Kynmobi)ApprovedSmall moleculedopamine
Crexont (IPX203)ApprovedSmall moleculedopamine precursor
Entacapone (Comtess)ApprovedSmall moleculeCOMT
Foslevodopa / Foscarbidopa (Vyalev)ApprovedSmall moleculedopamine precursor
Inbrija (CVT-301)ApprovedSmall moleculedopamine precursor
Istradefylline (Nourianz)ApprovedSmall moleculeadenosine A2A
Levodopa-Carbidopa Intestinal Gel (Duopa)ApprovedSmall moleculedopamine precursor
Opicapone (Ongentys)ApprovedSmall moleculeCOMT, PDE4
ParcopaApprovedSmall moleculedopamine precursor
Pimavanserin (Nuplazid)ApprovedSmall molecule5-HT2A/2C receptor, Serotonin 5-HT2A receptor (antagonist / inverse agonist)

…and 48 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (16)
Phase 2/3 (4)
Phase 2 (7)
Phase 1 (4)
Phase 4 (19)
Early phase / not applicable (1)
Used as active comparator (4)
Appears in other studies (1)