Asset profile

UB-312

Vaccine

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Earlyevidence

Evidence outlook

Early-stage evidence only

Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

65 competitors in this universe: 5 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 63 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
UB-312: this drugPhase 1Vaccinealpha-synuclein
PrasinezumabPhase 3Monoclonal antibodyalpha-synuclein
AFFITOPE PD01A / ACI-7104.056Phase 2Vaccinealpha-synuclein
ExidavnemabPhase 2Monoclonal antibodyalpha-synuclein
LY3962681Phase 1RNA / oligonucleotidealpha-synuclein
UCB7853Phase 1Biologic (subtype unspecified)alpha-synuclein
Amantadine ER (Gocovri / ADS-5102)ApprovedSmall moleculeNMDA receptor
Apomorphine (Apokyn)ApprovedSmall moleculedopamine
Apomorphine Sublingual Film (Kynmobi)ApprovedSmall moleculedopamine
Crexont (IPX203)ApprovedSmall moleculedopamine precursor
Entacapone (Comtess)ApprovedSmall moleculeCOMT
Foslevodopa / Foscarbidopa (Vyalev)ApprovedSmall moleculedopamine precursor
Inbrija (CVT-301)ApprovedSmall moleculedopamine precursor
Istradefylline (Nourianz)ApprovedSmall moleculeadenosine A2A
Levodopa-Carbidopa Intestinal Gel (Duopa)ApprovedSmall moleculedopamine precursor
Opicapone (Ongentys)ApprovedSmall moleculeCOMT, PDE4

…and 50 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.