Asset profile
Tonlamarsen
RNA / oligonucleotide
Evidence outlook · lead readout
NCT06864104 · Hypertension
The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.
NCT06864104: The study randomized 206 participants to tonlamarsen or placebo with participants, care providers, investigators, and outcome assessors masked. Its primary outcomes were changes in plasma angiotensinogen and seated systolic blood pressure at Week 20, but results are not posted, so whether either comparison was favorable cannot be determined.
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Upcoming events
(1 total)
Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.
2026 (1)
December 2026 (1)
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