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Company profile

Ionis Pharmaceuticals

Antisense oligonucleotide therapeutics

IONS · Nasdaq · USA

Share price · IONS

$43.54-38.26 (-46.77%) 3M

close as of 2026-10-02 · 24h delayed · vol 2.3M (0.6x 30-day avg)

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Prices are end-of-day (EOD), delayed by 24 hours · Adjusted for stock splits · Data via Databento

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Unusual price moves

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Assets

(17 total)
17Total Assets
6Approved
5Phase 3 / Filed
6Phase 1–2 / Early
14Diseases
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Showing 17 of 17 assets
Target & Modality
Donidalorsen(Dawnzera)
Approved
—RNA / oligonucleotide
Hereditary Angioedema
Eplontersen(Wainua)
Approved
—RNA / oligonucleotide
Transthyretin-Mediated Amyloidosis
Transthyretin Amyloidosis with Cardiomyopathy, Transthyretin Amyloidosis with Polyneuropathy
Inotersen(Tegsedi)
Approved
—RNA / oligonucleotide
Transthyretin-Mediated Amyloidosis
Transthyretin Amyloidosis with Polyneuropathy
Nusinersen(Spinraza)
Approved
—RNA / oligonucleotide
Spinal Muscular Atrophy
Olezarsen(Tryngolza)
Approved
APOC3RNA / oligonucleotide
Atherosclerotic Cardiovascular DiseaseFamilial Chylomicronemia SyndromeSevere Hypertriglyceridemia
Tofersen(Qalsody)
Approved
—RNA / oligonucleotide
Amyotrophic Lateral Sclerosis
Phase 3
—RNA / oligonucleotide
Angelman Syndrome
Phase 3
Apolipoprotein(a) mRNARNA / oligonucleotide
Atherosclerotic Cardiovascular Disease
Phase 3
—RNA / oligonucleotide
Amyotrophic Lateral Sclerosis
Volanesorsen(Waylivra)No recent activity
Phase 3
APOC3 mRNARNA / oligonucleotide
Atherosclerotic Cardiovascular DiseaseFamilial Chylomicronemia Syndrome
Phase 3
—RNA / oligonucleotide
Alexander Disease
Phase 2
MAPT mRNA (RNAi/ASO)RNA / oligonucleotide
Alzheimer's Disease
Phase 2
APOC3RNA / oligonucleotide
Atherosclerotic Cardiovascular Disease
ION904No recent activity
Phase 2
Angiotensinogen (AGT)RNA / oligonucleotide
Hypertension
Phase 2
Complement factor B (CFB)RNA / oligonucleotide
IgA Nephropathy

Upcoming events

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Financial reports

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Institutional holders

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Research includes quarterly SEC 13F institutional ownership: top holders, aggregate positions and quarter-over-quarter context.