Asset profile

Donidalorsen · Dawnzera

RNA / oligonucleotide

Approved / Phase 4Mechanism not established
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Approvedregulatory verdict

Evidence outlook

Approved: Hereditary Angioedema

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Competitive landscape

No competitors sharing a mechanism or indication in the current universe.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 3Hereditary AngioedemaActive not recruiting
Est. primary completion 2026-12 · NCT05392114 · CT.gov ↗
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2029 (1)
June 2029 (1)
Phase 3Hereditary AngioedemaRecruiting
Est. primary completion 2029-06 · NCT07298447 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (3)
Phase 2 (3)
Phase 1 (1)