Asset profile

N0877

Small molecule

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Stoppedregistry status

Evidence outlook

Development stopped: Phase 3 study withdrawn before enrolling

The drug's registered studies are all terminated, withdrawn or suspended (NCT06608472: withdrawn before enrolling); none completed, so no evidence signal is assigned. Check the registry record for the sponsor's stated reason.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 8 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
N0877: this drugPhase 3Small moleculeAngiotensin II receptor / Thiazide diuretic
Aprocitentan (Tryvio)ApprovedSmall moleculeEndothelin receptor (ETA/ETB, dual)
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)
Bosentan (Tracleer)ApprovedSmall moleculeEndothelin receptor (ETA/ETB, dual)
Epoprostenol (Flolan)ApprovedSmall moleculeIP receptor (prostacyclin pathway)
Nitric Oxide (INOmax)ApprovedGas (inhaled)Nitric oxide
Sacubitril / Valsartan (Entresto)ApprovedSmall moleculeNeprilysin + Angiotensin II receptor (dual)
Treprostinil (Orenitram / Remodulin / Tyvaso)ApprovedSmall moleculeIP receptor (prostacyclin pathway)
Treprostinil (Yutrepia, Liquidia)ApprovedSmall moleculeIP receptor (prostacyclin pathway)
AD-209Phase 3Small moleculeAngiotensin II type 1 receptor / L-type calcium channel / Na-Cl cotransporter
AGSAVIPhase 3Small moleculeAngiotensin II receptor / Calcium channel / Thiazide-like diuretic
AJU-C52Phase 3Small moleculeAngiotensin II receptor / Calcium channel / Thiazide-like diuretic
Ambrisentan (Letairis)Phase 3Small moleculeEndothelin A receptor
C2402Phase 3Small molecule—
CJ-30060Phase 3Small moleculeAngiotensin II receptor / Calcium channel / HMG-CoA reductase
CJ-30061Phase 3Small moleculeAngiotensin II receptor / Calcium channel / HMG-CoA reductase

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.