Asset profile

LB54640

Peptide

Partialsignal

Evidence outlook · lead readout

NCT06046443 · Hypothalamic Obesity

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT06046443: The study randomized 28 participants among three LB54640 dose groups and placebo, with participants, care providers, and investigators blinded. Its primary endpoint was mean percentage change in BMI at Week 14, but the result has not been reported, so whether the endpoint was met is unknown.

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