Asset profile

JZP926

Small molecule

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Phase 3underway

Evidence outlook · registrational

Epilepsy: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2028-08-01.

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Competitive landscape

62 competitors in this universe: 1 direct rival (same mechanism and indication), 1 same-class, 60 same-indication; 43 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
JZP926: this drugPhase 3Small moleculecannabinoid, Cannabidiol (CBD) modulates multiple targets, including the transient receptor potential vanilloid 1 (TRPV1) and the orphan G-protein-coupled receptor GPR55
Cannabidiol (Epidiolex)ApprovedSmall moleculeGPR55 / TRPV1 / adenosine transport (multi-target), cannabinoid
Cannabidiol (Kanbis)Phase 2Small moleculecannabinoid
BrivaracetamApprovedSmall moleculeSynaptic vesicle glycoprotein 2A (SV2A)
CarbamazepineApprovedSmall moleculeSodium channels
Cenobamate (Xcopri)ApprovedSmall moleculeSodium channels + GABA-A receptors
Clobazam (Onfi)ApprovedSmall moleculeGABA-A receptor
Clobazam (Sympazan)ApprovedSmall moleculeGABA-A receptor (benzodiazepine site)
DiastatApprovedCombinationGABA-A receptor
Diazepam (Valium)ApprovedSmall moleculeGABA-A receptor
Diazepam (Valtoco)ApprovedSmall moleculeGABA-A receptor
Divalproex Sodium (Depakote)ApprovedSmall moleculeGABAergic neurotransmission
Eslicarbazepine Acetate (Aptiom)ApprovedSmall moleculeVoltage-gated sodium channel
EthosuximideApprovedSmall moleculeT-type calcium channel
EverolimusApprovedSmall moleculemTOR kinase, mTOR (mTORC1) (inhibitor)
Ezogabine (Potiga)ApprovedSmall moleculeKv7 potassium channel

…and 47 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
November 2027 (1)
Phase 1EpilepsyRecruiting
Est. primary completion 2027-11-29 · NCT07233239 · CT.gov ↗
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2028 (2)
August 2028 (1)
Phase 2/3EpilepsyNot yet recruiting
Est. primary completion 2028-08-01 · NCT07723963 · CT.gov ↗
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December 2028 (1)
Phase 4EpilepsyNot yet recruiting
Est. primary completion 2028-12-28 · NCT07728097 · CT.gov ↗
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2029 (1)
September 2029 (1)
Phase 3EpilepsyNot yet recruiting
Est. primary completion 2029-09-04 · NCT07723976 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (3)
Phase 2/3 (1)
Phase 2 (1)
Phase 1 (1)
Phase 4 (1)