Asset profile
ION904
RNA / oligonucleotide
Evidence outlook · lead readout
NCT05314439 · Hypertension
The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.
NCT05314439: The study randomly assigned 48 participants to ION904 or placebo and masked participants, investigators, and outcome assessors. However, its primary endpoint was the surrogate biomarker plasma angiotensinogen, and no primary endpoint results have been posted.
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