Asset profile

Treprostinil · Orenitram / Remodulin / Tyvaso

Peptide

Approvedregulatory verdict

Evidence outlook

Approved — Hypertension

Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
December 2026 (2)
Phase 2COPD (Chronic Obstructive Pulmonary Disease)Active not recruiting
Est. primary completion 2026-12-31 · NCT06969573 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 2/3Pulmonary Arterial HypertensionActive not recruiting
Est. primary completion 2026-12-31 · NCT05649748 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2027 (2)
July 2027 (1)
Phase 2COPD (Chronic Obstructive Pulmonary Disease), HypoxemiaRecruiting
Est. primary completion 2027-07-01 · NCT07037836 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2027 (1)
Phase 2HypertensionNot yet recruiting
Est. primary completion 2027-12-31 · NCT07177703 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (3)
November 2028 (1)
Phase 3Pulmonary Arterial HypertensionRecruiting
Est. primary completion 2028-11 · NCT06350032 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2028 (2)
Phase 3Pulmonary Arterial HypertensionRecruiting
Est. primary completion 2028-12-28 · NCT07481981 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Pulmonary Hypertension, Interstitial Lung DiseaseRecruiting
Est. primary completion 2028-12-30 · NCT07179380 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2031 (1)
January 2031 (1)
Phase 3Pulmonary Hypertension, Interstitial Lung DiseaseRecruiting
Est. primary completion 2031-01-22 · NCT07234032 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

Research

Unlock the complete ClinicalTrials.gov registry

Research includes every linked study, indication filters, phase grouping and featured-trial cross-links.

Competitive landscape

Research

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Research compares assets by shared mechanism and indication, including each competitor's stage in the relevant market.