Asset profile

AJU-C52

Small molecule

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Phase 3underway

Evidence outlook · registrational

Hypertension: registrational trials complete, results ungraded

Its supporting mid-stage evidence has not yet been graded on this platform. Its registrational studies have completed; results have not been graded on this platform. Check News and the registry record for topline outcomes.

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Competitive landscape

61 competitors in this universe: 1 direct rival (same mechanism and indication), 0 same-class, 60 same-indication; 8 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
AJU-C52: this drugPhase 3Small moleculeAngiotensin II receptor / Calcium channel / Thiazide-like diuretic
AGSAVIPhase 3Small moleculeAngiotensin II receptor / Calcium channel / Thiazide-like diuretic
Aprocitentan (Tryvio)ApprovedSmall moleculeEndothelin receptor (ETA/ETB, dual)
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)
Bosentan (Tracleer)ApprovedSmall moleculeEndothelin receptor (ETA/ETB, dual)
Epoprostenol (Flolan)ApprovedSmall moleculeIP receptor (prostacyclin pathway)
Nitric Oxide (INOmax)ApprovedGas (inhaled)Nitric oxide
Sacubitril / Valsartan (Entresto)ApprovedSmall moleculeNeprilysin + Angiotensin II receptor (dual)
Treprostinil (Orenitram / Remodulin / Tyvaso)ApprovedSmall moleculeIP receptor (prostacyclin pathway)
Treprostinil (Yutrepia, Liquidia)ApprovedSmall moleculeIP receptor (prostacyclin pathway)
AD-209Phase 3Small moleculeAngiotensin II type 1 receptor / L-type calcium channel / Na-Cl cotransporter
Ambrisentan (Letairis)Phase 3Small moleculeEndothelin A receptor
C2402Phase 3Small molecule—
CJ-30060Phase 3Small moleculeAngiotensin II receptor / Calcium channel / HMG-CoA reductase
CJ-30061Phase 3Small moleculeAngiotensin II receptor / Calcium channel / HMG-CoA reductase
DWC202206 + DWC202207Phase 3Small molecule—

…and 46 more. Research shows the complete landscape.

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Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.