Asset profile

GPC-100

Small molecule

Partialsignal

Evidence outlook · lead readout

NCT05561751 · Multiple Myeloma

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT05561751: The study randomized 30 patients to two open-label treatment regimens, but it was not blinded and had no placebo or standard-treatment control arm. Its primary endpoint was the proportion achieving a target number of CD34+ cells during leukapheresis, a surrogate mobilization measure, and no results are available to show whether the endpoint was met.

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