Asset profile

CT-996

Small molecule

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Partialdesign only

Evidence outlook · results not reported

NCT07081958 · Obesity or Overweight

The lead study's design has limits that temper confidence (see the rationale below), and its results have not been reported. This tier describes the design, not an outcome.

NCT07081958: The study randomized 352 participants to placebo or one of seven RO7795081 dosing regimens, with participants and investigators blinded. Its primary endpoint was the clinical measure of percent change in body weight at Week 30, but no results or statistical comparison have been posted, so the endpoint cannot yet be classified as met or missed.

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Competitive landscape

110 competitors in this universe: 34 direct rivals (same mechanism and indication), 16 same-class, 60 same-indication; 66 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
CT-996: this drugPhase 2Small moleculeGLP-1 receptor
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Orforglipron (Foundayo)ApprovedSmall moleculeGLP-1 receptor
Semaglutide (Wegovy / Ozempic / Rybelsus)ApprovedPeptideGLP-1 receptor
AleniglipronPhase 3Small moleculeGLP-1 receptor
AmycretinPhase 3PeptideGLP-1 receptor, Amylin receptor
ASC30Phase 3Small moleculeGLP-1 receptor
Cagrilintide / Semaglutide (CagriSema)Phase 3PeptideAmylin receptor, GLP-1 receptor
CX11Phase 3Small moleculeGLP-1 receptor
DA-302168SPhase 3Small moleculeGLP-1 receptor
EcnoglutidePhase 3PeptideGLP-1 receptor
ElecoglipronPhase 3Small moleculeGLP-1 receptor
EnicepatidePhase 3PeptideGLP-1 receptor, GLP-1/GIP receptor (dual)
GZR18Phase 3PeptideGLP-1 receptor
HDM1002Phase 3Small moleculeGLP-1 receptor
HRS-7535Phase 3Small moleculeGLP-1 receptor

…and 95 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

28 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
November 2026 (1)
Phase 2Type 2 Diabetes MellitusActive not recruiting
Est. primary completion 2026-11-27 · NCT07112872 · CT.gov ↗
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December 2026 (1)
Phase 1ObesityActive not recruiting
Est. primary completion 2026-12-07 · NCT06982131 · CT.gov ↗
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2027 (1)
January 2027 (1)
Phase 1ObesityActive not recruiting
Est. primary completion 2027-01-09 · NCT07499050 · CT.gov ↗
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2028 (1)
February 2028 (1)
Phase 1Renal ImpairmentRecruiting
Est. primary completion 2028-02-01 · NCT07741604 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (2)
Phase 1 (5)