Asset profile

GZR18

Peptide

Phase 3underway

Evidence outlook · registrational

Obesity: registrational readout pending

Entered Phase 3 on partial signal mid-stage evidence. Registrational readout expected around 2027-06-30.

NCT06737042: The study randomized 326 participants and used quadruple masking with placebo and tirzepatide comparator arms; its primary endpoint was the clinical outcome of percentage change in body weight. Because the primary comparison has not yet been reported, it cannot establish whether GZR18 met its efficacy objective.

How the evidence outlook works ↗

Upcoming events

(5 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (4)
June 2027 (1)
Phase 3ObesityRecruiting
Est. primary completion 2027-06-30 · NCT07150975 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

September 2027 (1)
Phase 3ObesityRecruiting
Est. primary completion 2027-09 · NCT07292441 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

November 2027 (1)
Phase 3Obstructive Sleep Apnea (OSA)Not yet recruiting
Est. primary completion 2027-11-14 · NCT07493057 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2027 (1)
Phase 3ObesityNot yet recruiting
Est. primary completion 2027-12 · NCT07622810 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (1)
September 2028 (1)
Phase 3Obstructive Sleep Apnea (OSA)Not yet recruiting
Est. primary completion 2028-09-28 · NCT07501832 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

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