Asset profile

ZL-1102

Monoclonal antibody

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Stoppedregistry status

Evidence outlook

Development stopped: Phase 2 study terminated

The drug's registered studies are all terminated, withdrawn or suspended (NCT06380907: terminated); none completed, so no evidence signal is assigned. Check the registry record for the sponsor's stated reason.

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Competitive landscape

62 competitors in this universe: 2 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 50 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
ZL-1102: this drugPhase 2Monoclonal antibodyIL-17A
HB0017Phase 3Monoclonal antibodyIL-17A
UA026Phase 1Small moleculeIL-17A
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Apremilast (Otezla)ApprovedSmall moleculePDE4
Bimekizumab (Bimzelx)ApprovedMonoclonal antibodyIL-17A/F
Brepocitinib (Lisraya)ApprovedSmall moleculeTYK2/JAK1
Brodalumab (Siliq)ApprovedMonoclonal antibodyIL-17 receptor A
Calcipotriene / Betamethasone Dipropionate Cream (Wynzora)ApprovedSmall moleculeVitamin D receptor + Glucocorticoid receptor
Calcipotriene / Betamethasone Dipropionate Foam (Enstilar)ApprovedSmall moleculeVitamin D receptor + Glucocorticoid receptor
Certolizumab Pegol (Cimzia)ApprovedAntibody fragmentTNF-alpha
Desoximetasone (Topicort Spray)ApprovedSmall moleculeGlucocorticoid receptor agonist
Deucravacitinib (Sotyktu)ApprovedSmall moleculeTYK2
Etanercept (Enbrel)ApprovedProtein / enzyme therapeuticTNF-alpha, TNF-alpha / TNF-beta (lymphotoxin-alpha)
Guselkumab (Tremfya)ApprovedMonoclonal antibodyIL-23 p19
Halobetasol Propionate Foam (Lexette)ApprovedSmall moleculeGlucocorticoid receptor

…and 47 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.