Head-to-head evidence

HB0017 vs ZL-1102

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Psoriasis

Shared mechanism: IL-17A · full Psoriasis pipeline

HB0017

Developed by Huabo Biopharm Co.

Phase 3 in Psoriasismonoclonal antibody
Partial signal

NCT06477237 · Phase 3 · status unknown

This is a randomized, quadruple-blind, placebo-controlled Phase 3 trial using validated psoriasis response measures as its primary endpoints, but no results are yet posted to the registry, so the outcome is unknown.

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ZL-1102

Developed by Zai Lab

Phase 2 in Psoriasismonoclonal antibody
Partial signal

NCT06380907 · Phase 2 · terminated

This is a randomized, quadruple-blind, placebo-controlled study using the standard validated measure of psoriasis severity as its primary endpoint, but it enrolled only 65 patients spread across five dose and placebo arms, and results have not yet been reported. The design is sound, but the small group size and the lack of posted results mean the treatment effect is not yet established.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: HB0017's landscape · ZL-1102's landscape