Asset profile

Ubrogepant (Ubrelvy)

Small molecule

Approved / Phase 4Mechanism not established
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Approvedregulatory verdict

Evidence outlook

Approved: Migraine

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Competitive landscape

52 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 52 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Ubrogepant (Ubrelvy): this drugApprovedSmall molecule—
Almotriptan (Axert)ApprovedSmall molecule—
Aspirin / Acetaminophen / Caffeine (Excedrin Migraine)Approved——
Atogepant (Qulipta)ApprovedSmall molecule—
Celecoxib (Elyxyb)ApprovedSmall molecule—
Diclofenac Potassium (Cambia)ApprovedSmall moleculeNonsteroidal Anti-inflammatory Drug
Dihydroergotamine (Atzumi)Approved——
Dihydroergotamine Mesylate (Brekiya)Approved——
Dihydroergotamine Mesylate (D.H.E. 45)Approved——
Dihydroergotamine Mesylate (Migranal)Approved——
Divalproex Sodium (Depakote ER)Approved—GABAergic neurotransmission
Divalproex Sodium (Depakote)ApprovedSmall moleculeGABAergic neurotransmission
Eletriptan (Relpax)ApprovedSmall molecule—
Eptinezumab (Vyepti)ApprovedMonoclonal antibody—
Erenumab (Aimovig)ApprovedMonoclonal antibody—
Ergotamine / Caffeine (Cafergot)Approved——

…and 37 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
May 2027 (1)
Phase 3MigraineRecruiting
Est. primary completion 2027-05 · NCT05125302 · CT.gov ↗
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November 2027 (1)
Phase 3MigraineActive not recruiting
Est. primary completion 2027-11 · NCT06417775 · CT.gov ↗
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2028 (1)
January 2028 (1)
Phase 3MigraineEnrolling by invitation
Est. primary completion 2028-01 · NCT05127954 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (7)
Phase 1 (3)
Phase 4 (2)
Early phase / not applicable (1)
Used as active comparator (1)