Asset profile

Dihydroergotamine mesylate (Migranal)

Unknown / undisclosed

Approved / Phase 4Mechanism not established
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Approvedregulatory verdict

Evidence outlook

Approved: Migraine

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

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Competitive landscape

52 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 52 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Dihydroergotamine Mesylate (Migranal): this drugApproved——
Almotriptan (Axert)ApprovedSmall molecule—
Aspirin / Acetaminophen / Caffeine (Excedrin Migraine)Approved——
Atogepant (Qulipta)ApprovedSmall molecule—
Celecoxib (Elyxyb)ApprovedSmall molecule—
Diclofenac Potassium (Cambia)ApprovedSmall moleculeNonsteroidal Anti-inflammatory Drug
Dihydroergotamine (Atzumi)Approved——
Dihydroergotamine Mesylate (Brekiya)Approved——
Dihydroergotamine Mesylate (D.H.E. 45)Approved——
Divalproex Sodium (Depakote ER)Approved—GABAergic neurotransmission
Divalproex Sodium (Depakote)ApprovedSmall moleculeGABAergic neurotransmission
Eletriptan (Relpax)ApprovedSmall molecule—
Eptinezumab (Vyepti)ApprovedMonoclonal antibody—
Erenumab (Aimovig)ApprovedMonoclonal antibody—
Ergotamine / Caffeine (Cafergot)Approved——
Fremanezumab (Ajovy)ApprovedMonoclonal antibody—

…and 37 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

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Research includes every linked study, indication filters, phase grouping and featured-trial cross-links.