Asset profile

Dihydroergotamine mesylate/Dipyrone/Caffeine (Cefaliv)

Unknown / undisclosed

Mechanism not establishedNo recent registered activity
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Approvedregulatory verdict

Evidence outlook

Approved: the acute treatment of migraine headaches with or without aura and the acute treatment of... (FDA)

This approval is for an indication outside this terminal's covered markets; the covered program shown here is investigational. Regulatory approval supersedes design-level evidence grading for the approved use.

Source for the program status

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Competitive landscape

52 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 52 same-indication; 51 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Dihydroergotamine Mesylate / Dipyrone / Caffeine (Cefaliv): this drugNot yet studied——
Almotriptan (Axert)ApprovedSmall molecule—
Aspirin / Acetaminophen / Caffeine (Excedrin Migraine)Approved——
Atogepant (Qulipta)ApprovedSmall molecule—
Celecoxib (Elyxyb)ApprovedSmall molecule—
Diclofenac Potassium (Cambia)ApprovedSmall moleculeNonsteroidal Anti-inflammatory Drug
Dihydroergotamine (Atzumi)Approved——
Dihydroergotamine Mesylate (Brekiya)Approved——
Dihydroergotamine Mesylate (D.H.E. 45)Approved——
Dihydroergotamine Mesylate (Migranal)Approved——
Divalproex Sodium (Depakote ER)Approved—GABAergic neurotransmission
Divalproex Sodium (Depakote)ApprovedSmall moleculeGABAergic neurotransmission
Eletriptan (Relpax)ApprovedSmall molecule—
Eptinezumab (Vyepti)ApprovedMonoclonal antibody—
Erenumab (Aimovig)ApprovedMonoclonal antibody—
Ergotamine / Caffeine (Cafergot)Approved——

…and 37 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.