Asset profile
Dihydroergotamine mesylate (D.H.E. 45)
Unknown / undisclosed
Evidence outlook
Approved: Migraine
Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.
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Featured trials
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Competitive landscape
52 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 52 same-indication.
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| Dihydroergotamine Mesylate (D.H.E. 45): this drug | Approved | — | — | ||
| Almotriptan (Axert) | Approved | Small molecule | — | ||
| Aspirin / Acetaminophen / Caffeine (Excedrin Migraine) | Approved | — | — | ||
| Atogepant (Qulipta) | Approved | Small molecule | — | ||
| Celecoxib (Elyxyb) | Approved | Small molecule | — | ||
| Diclofenac Potassium (Cambia) | Approved | Small molecule | Nonsteroidal Anti-inflammatory Drug | ||
| Dihydroergotamine (Atzumi) | Approved | — | — | ||
| Dihydroergotamine Mesylate (Brekiya) | Approved | — | — | ||
| Dihydroergotamine Mesylate (Migranal) | Approved | — | — | ||
| Divalproex Sodium (Depakote ER) | Approved | — | GABAergic neurotransmission | ||
| Divalproex Sodium (Depakote) | Approved | Small molecule | GABAergic neurotransmission | ||
| Eletriptan (Relpax) | Approved | Small molecule | — | ||
| Eptinezumab (Vyepti) | Approved | Monoclonal antibody | — | ||
| Erenumab (Aimovig) | Approved | Monoclonal antibody | — | ||
| Ergotamine / Caffeine (Cafergot) | Approved | — | — | ||
| Fremanezumab (Ajovy) | Approved | Monoclonal antibody | — |
…and 37 more. Research shows the complete landscape.
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Upcoming events
No upcoming readouts on record for this asset.
All registered studies
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