Asset profile

TED-A9 (A9-DPC)

Cell therapy

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Weakdesign only

Evidence outlook · results not reported

NCT05887466 · Parkinson's Disease

The lead study uses a design that frequently fails to replicate under controlled conditions, and its results have not been reported. This tier describes the design, not an outcome.

NCT05887466: The study assigned six participants to each of two dose groups without randomization, blinding, or a placebo or active comparator. Its primary outcomes focused on adverse events and transplant failure or rejection. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

Caveat: this result is taken from a company announcement or a news report of one, not from the trial registry or a peer-reviewed publication. Treat the figures as the sponsor's own statement, not as independently verified evidence.

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Competitive landscape

66 competitors in this universe: 6 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 61 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
TED-A9 (A9-DPC): this drugPhase 1/2Cell therapydopaminergic neuron replacement
NouvNeu001Phase 2Cell therapydopaminergic neuron replacement
RNDP-001Phase 1/2Cell therapydopaminergic neuron replacement
XS-411Phase 1/2Cell therapydopaminergic neuron replacement
ANPD001Phase 1Cell therapydopaminergic neuron replacement
iPS-NSC CellsPhase 1Cell therapydopaminergic neuron replacement
UX-DA001Phase 1Cell therapydopaminergic neuron replacement
Amantadine ER (Gocovri / ADS-5102)ApprovedSmall moleculeNMDA receptor
Apomorphine (Apokyn)ApprovedSmall moleculedopamine
Apomorphine Sublingual Film (Kynmobi)ApprovedSmall moleculedopamine
Crexont (IPX203)ApprovedSmall moleculedopamine precursor
Entacapone (Comtess)ApprovedSmall moleculeCOMT
Foslevodopa / Foscarbidopa (Vyalev)ApprovedSmall moleculedopamine precursor
Inbrija (CVT-301)ApprovedSmall moleculedopamine precursor
Istradefylline (Nourianz)ApprovedSmall moleculeadenosine A2A
Levodopa-Carbidopa Intestinal Gel (Duopa)ApprovedSmall moleculedopamine precursor

…and 51 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2029 (1)
February 2029 (1)
Phase not recordedParkinson's DiseaseActive not recruiting
Est. primary completion 2029-02-07 · NCT06477744 · CT.gov ↗
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.