Asset profile

SAR443579

Biologic (subtype unspecified)

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Stoppedregistry status

Evidence outlook

Development stopped: Phase 1/2 study terminated

The drug's registered studies are all terminated, withdrawn or suspended (NCT06508489: terminated); none completed, so no evidence signal is assigned. Check the registry record for the sponsor's stated reason.

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Competitive landscape

66 competitors in this universe: 6 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 39 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
SAR443579: this drugPhase 1/2Biologic (subtype unspecified)CD123
Pivekimab SunirinePhase 2/3Antibody–drug conjugateCD123
TagraxofuspPhase 2—CD123
CD123 Targeted CAR-NK CellsPhase 1/2Cell therapyCD123
Allo-RevCAR01-TPhase 1—CD123
Anti-CD123 CAR NK CellsPhase 1—CD123
BYON4413Phase 1—CD123
ASTX727ApprovedSmall moleculeDecitabine/cedazuridine fixed combination (DNMT + CDA inhibition)
EnasidenibApprovedSmall moleculeIDH2
Gemtuzumab OzogamicinApprovedAntibody–drug conjugateCD33
GilteritinibApprovedSmall moleculeFLT3
MidostaurinApprovedSmall moleculeFLT3;KIT;PKC;PDGFR
OlutasidenibApprovedSmall moleculeMutant IDH1
QuizartinibApprovedSmall moleculeFLT3
RevumenibApprovedSmall moleculeMenin
Tretinoin (Vesanoid)ApprovedSmall moleculeRARA (retinoic acid receptor alpha); degrades the PML-RARA fusion oncoprotein in APL

…and 51 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.