Asset profile

L-DOS47

Monoclonal antibody

Phase 2CEACAM6No recent registered activity
Weaksignal

Evidence outlook · lead readout

NCT02340208 · Non-Small Cell Lung Cancer

The reported results come from study designs that frequently fail to replicate under controlled conditions — see the rationale below.

NCT02340208: The study was open-label, non-randomized, and had no comparator arm; all 76 participants received dose-escalating L-DOS47. Its primary endpoint concerned treatment-related adverse events and tolerability, and results were not posted, so there is no reported primary comparison or evidence of benefit.

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