Asset profile
ION251
RNA / oligonucleotide
Evidence outlook · lead readout
NCT04398485 · Relapsed Multiple Myeloma, Refractory Multiple Myeloma
The reported results come from study designs that frequently fail to replicate under controlled conditions — see the rationale below.
NCT04398485: This was an open-label, single-arm dose-finding study with no randomization, no blinding, and no control group, aimed at establishing a tolerated dose rather than testing efficacy. Results have not yet been reported.
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