Asset profile

ICP-332

Small molecule

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Phase 3underway

Evidence outlook · registrational

Atopic Dermatitis: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2026-11-25.

Also in development:Psoriasis · Phase 2

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Competitive landscape

118 competitors in this universe: 3 direct rivals (same mechanism and indication), 1 same-class, 114 same-indication; 36 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
ICP-332: this drugPhase 3Small moleculeTYK2/JAK1
Brepocitinib (Lisraya)ApprovedSmall moleculeTYK2/JAK1
TLL-018Phase 3Small moleculeTYK2/JAK1
TDM-180935Phase 2Small moleculeTYK2/JAK1
BHV-8000Phase 2/3Small moleculeTYK2/JAK1
Abrocitinib (Cibinqo)ApprovedSmall moleculeJAK1
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Apremilast (Otezla)ApprovedSmall moleculePDE4
Baricitinib (Olumiant)ApprovedSmall moleculeJAK, JAK1/2
Bimekizumab (Bimzelx)ApprovedMonoclonal antibodyIL-17A/F
Brodalumab (Siliq)ApprovedMonoclonal antibodyIL-17 receptor A
Calcipotriene / Betamethasone Dipropionate Cream (Wynzora)ApprovedSmall moleculeVitamin D receptor + Glucocorticoid receptor
Calcipotriene / Betamethasone Dipropionate Foam (Enstilar)ApprovedSmall moleculeVitamin D receptor + Glucocorticoid receptor
Certolizumab Pegol (Cimzia)ApprovedAntibody fragmentTNF-alpha
Crisaborole (Eucrisa)ApprovedSmall moleculePDE4
Desoximetasone (Topicort Spray)ApprovedSmall moleculeGlucocorticoid receptor agonist

…and 103 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
November 2026 (1)
Phase 3Atopic DermatitisRecruiting
Est. primary completion 2026-11-25 · NCT06775860 · CT.gov ↗
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2027 (1)
March 2027 (1)
Phase 2Prurigo Nodularis (PN)Recruiting
Est. primary completion 2027-03 · NCT07236099 · CT.gov ↗
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2028 (1)
September 2028 (1)
Phase 2/3Chronic Spontaneous Urticaria (CSU)Recruiting
Est. primary completion 2028-09 · NCT07378527 · CT.gov ↗
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2029 (1)
April 2029 (1)
Phase 2/3Non Segmental VitiligoRecruiting
Est. primary completion 2029-04 · NCT07047612 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2/3 (2)
Phase 2 (3)
Phase 1 (2)