Asset profile

GRI-0803

Small molecule

Mechanism not established
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—preclinical

Evidence outlook

No clinical-stage evidence registered

No clinical trials are registered for this drug yet, so there is nothing to grade.

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Competitive landscape

54 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 54 same-indication; 54 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
GRI-0803: this drugNot yet studiedSmall molecule—
AnifrolumabApprovedMonoclonal antibodyType I interferon receptor, Type I interferon receptor subunit 1 (IFNAR1)
Avacopan (Tavneos)ApprovedSmall moleculeComplement C5a receptor 1 (C5aR1/CD88)
Belimumab (GSK1550188)ApprovedMonoclonal antibodyBAFF / BLyS (B-lymphocyte stimulator), BAFF (BLyS)
Deucravacitinib (Sotyktu)ApprovedSmall moleculeTYK2
Repository Corticotropin (Acthar Gel)ApprovedPeptideMelanocortin receptors (primarily MC2R on the adrenal cortex), Melanocortin 2 receptor (MC2R) (agonist)
Upadacitinib (Rinvoq)ApprovedSmall moleculeJAK, JAK1
Voclosporin (Lupkynis)ApprovedSmall moleculeCalcineurin, Cyclophilin A (leading to calcineurin inhibition)
APG-2575(Lisaftoclax )Phase 3Small moleculeBCL-2
AZD0120Phase 3Cell therapyBCMA / CD19
BlinatumomabPhase 3Multispecific antibodyCD19 x CD3
Descartes-08Phase 3Cell therapy—
DivozilimabPhase 3Monoclonal antibodyCD20
EnvudeucitinibPhase 3Small moleculeTYK2
FrexalimabPhase 3Monoclonal antibodyCD40 ligand (CD40L / CD154)
InebilizumabPhase 3Monoclonal antibodyCD19

…and 39 more. Research shows the complete landscape.

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Upcoming events

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All registered studies

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