Asset profile

Goserelin

Peptide

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Approvedregulatory verdict

Evidence outlook

Approved: HR+/HER2- Metastatic Breast Cancer

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Goserelin: this drugApprovedPeptideGnRH receptor (agonist)
Abemaciclib (Verzenio)ApprovedSmall moleculeCDK4 and CDK6
Alpelisib (BYL719)ApprovedSmall moleculePI3K-alpha
AnastrozoleApprovedSmall moleculeAromatase
CapecitabineApprovedSmall moleculeFluoropyrimidine (antimetabolite)
CapivasertibApprovedSmall moleculeAKT (inhibitor)
Datopotamab DeruxtecanApprovedAntibody–drug conjugateTROP2
DenosumabApprovedMonoclonal antibodyRANKL
DocetaxelApprovedSmall moleculeMicrotubules (tubulin)
ElacestrantApprovedSmall moleculeEstrogen receptor
Eribulin MesylateApprovedSmall moleculeTubulin / microtubules
EverolimusApprovedSmall moleculemTOR kinase, mTOR (mTORC1) (inhibitor)
ExemestaneApprovedSmall moleculeAromatase
Fulvestrant (Faslodex)ApprovedSmall moleculeEstrogen receptor
GedatolisibApprovedSmall moleculePI3K (class I isoforms) and mTORC1/mTORC2
GemcitabineApprovedSmall moleculeribonucleotide reductase / DNA polymerase (dCTP competition)

…and 45 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(33 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (4)
November 2026 (2)
Phase 2HR+/HER2- Metastatic Breast CancerActive not recruiting
Est. primary completion 2026-11 · NCT05607004 · CT.gov ↗
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Phase 3Prostate AdenocarcinomaActive not recruiting
Est. primary completion 2026-11-11 · NCT05050084 · CT.gov ↗
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December 2026 (2)
Phase 2Triple Negative Breast Cancer, Premenopausal Breast CancerRecruiting
Est. primary completion 2026-12 · NCT06225284 · CT.gov ↗
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Phase 1HR+/HER2- Metastatic Breast CancerActive not recruiting
Est. primary completion 2026-12-30 · NCT05870579 · CT.gov ↗
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2027 (13)
January 2027 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2027-01-31 · NCT02476786 · CT.gov ↗
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February 2027 (1)
Phase 2Prostate Adenocarcinoma, Recurrent Prostate CarcinomaActive not recruiting
Est. primary completion 2027-02-01 · NCT01786265 · CT.gov ↗
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March 2027 (2)
Phase 3Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8 …Active not recruiting
Est. primary completion 2027-03-15 · NCT04455750 · CT.gov ↗
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Phase 1HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2027-03-30 · NCT07310420 · CT.gov ↗
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April 2027 (2)
Phase 2/3Castration-resistant Prostate Cancer Patients with OligometastasesActive not recruiting
Est. primary completion 2027-04 · NCT02685397 · CT.gov ↗
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Phase 4Metabolic Dysfunction-Associated Steatotic Liver Disease, Nonalcoholic Fatty Liver, EndometriosisActive not recruiting
Est. primary completion 2027-04 · NCT06523530 · CT.gov ↗
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May 2027 (3)
Early phase / not applicableAllogeneic Haematopoietic Stem Cell Transplantation, Malignant Hematologic Disease, Ovarian InsufficiencyNot yet recruiting
Est. primary completion 2027-05-01 · NCT07552480 · CT.gov ↗
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Early phase / not applicableAplastic Anaemia (AA), Allogeneic Haematopoietic Stem Cell Transplantation, Ovarian InsufficiencyNot yet recruiting
Est. primary completion 2027-05-01 · NCT07552506 · CT.gov ↗
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Early phase / not applicableOvarian Insufficiency, Autologous Hematopoietic Stem Cell TransplantationNot yet recruiting
Est. primary completion 2027-05-01 · NCT07552493 · CT.gov ↗
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August 2027 (3)
Phase 4Musculoskeletal Injury, Hypogonadism, Hormonal ContraceptionRecruiting
Est. primary completion 2027-08 · NCT06455969 · CT.gov ↗
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Phase 2Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8 …Recruiting
Est. primary completion 2027-08-23 · NCT04734730 · CT.gov ↗
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Phase 2Prostate CancerRecruiting
Est. primary completion 2027-08-31 · NCT06582446 · CT.gov ↗
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December 2027 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2027-12-31 · NCT05582499 · CT.gov ↗
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2028 (6)
January 2028 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2028-01-01 · NCT07158021 · CT.gov ↗
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April 2028 (1)
Phase 3Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma, Stage IV Prostate Cancer AJCC v8 …Recruiting
Est. primary completion 2028-04-01 · NCT03678025 · CT.gov ↗
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July 2028 (1)
Phase 2Salivary Gland Carcinoma, Precision TherapyRecruiting
Est. primary completion 2028-07-10 · NCT06145308 · CT.gov ↗
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September 2028 (2)
Phase 1/2HR+/HER2- Metastatic Breast CancerNot yet recruiting
Est. primary completion 2028-09 · NCT07596212 · CT.gov ↗
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Phase 2HR+/HER2- Metastatic Breast CancerNot yet recruiting
Est. primary completion 2028-09-30 · NCT07801898 · CT.gov ↗
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December 2028 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2028-12-21 · NCT07460752 · CT.gov ↗
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2029 (2)
January 2029 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2029-01 · NCT07287098 · CT.gov ↗
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September 2029 (1)
Phase 3HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2029-09-07 · NCT05827081 · CT.gov ↗
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2030 (4)
June 2030 (1)
Phase 4HR+/HER2- Metastatic Breast CancerActive not recruiting
Est. primary completion 2030-06-28 · NCT05161195 · CT.gov ↗
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July 2030 (1)
Phase 2/3Prostate CancerRecruiting
Est. primary completion 2030-07-31 · NCT06282588 · CT.gov ↗
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September 2030 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2030-09 · NCT06953882 · CT.gov ↗
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December 2030 (1)
Phase 2HER2-positive Breast CancerNot yet recruiting
Est. primary completion 2030-12-30 · NCT07179939 · CT.gov ↗
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2032 (1)
December 2032 (1)
Phase 3Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma, Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8Recruiting
Est. primary completion 2032-12-31 · NCT04423211 · CT.gov ↗
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2033 (1)
December 2033 (1)
Phase 3Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8Active not recruiting
Est. primary completion 2033-12-31 · NCT04513717 · CT.gov ↗
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2034 (1)
July 2034 (1)
Phase 2Human Epidermal Growth Factor 2 Negative Carcinoma of Breast, HER2-positive Breast Cancer, Breast CancerRecruiting
Est. primary completion 2034-07-01 · NCT06348134 · CT.gov ↗
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2035 (1)
October 2035 (1)
Phase 3High Risk Prostate CancerNot yet recruiting
Est. primary completion 2035-10 · NCT07777263 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (75)
Phase 2/3 (7)
Phase 2 (103)
Phase 1/2 (7)
Phase 1 (21)
Phase 4 (19)
Early phase / not applicable (17)
Used as active comparator (20)
Appears in other studies (4)