Asset profile
Giredestrant
Small molecule
Evidence outlook · registrational
HR+/HER2- Metastatic Breast Cancer: registrational readout pending
Entered Phase 3 on partial signal mid-stage evidence. Registrational readout expected around 2027-02-19.
NCT04436744: This was a randomized but unblinded trial of 221 patients using a tumor biomarker (Ki67), rather than a hard clinical outcome such as tumor response or survival, as its primary measure; the giredestrant combination produced a statistically significant reduction in this biomarker compared with the anastrozole combination.
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Upcoming events
(7 total)
Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.
2027 (2)
February 2027 (1)
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June 2028 (1)
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May 2029 (1)
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September 2030 (1)
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June 2032 (1)
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