Asset profile

rESP

Biologic (subtype unspecified)

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Phase 3underway

Evidence outlook · registrational

Chronic Kidney Disease: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. The registry's posted readout date (2023-06-30) has passed without a status update. Check News for topline announcements.

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Competitive landscape

64 competitors in this universe: 4 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 25 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
rESP: this drugPhase 3Biologic (subtype unspecified)Erythropoietin receptor (EPO-R)
JR-131Phase 3Biologic (subtype unspecified)Erythropoietin receptor (EPO-R)
NNG-DEPO (Stimus)Phase 3Biologic (subtype unspecified)Erythropoietin receptor (EPO-R)
Pegmolesatide (HS-20039)Phase 3PeptideErythropoietin receptor (EPO-R)
RD01 (PEG-EPO)Phase 2Biologic (subtype unspecified)Erythropoietin receptor (EPO-R)
Atrasentan (Vanrafia)ApprovedSmall moleculeEndothelin A receptor
Avacopan (Tavneos)ApprovedSmall moleculeComplement C5a receptor 1 (C5aR1/CD88)
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)
Budesonide (targeted-Release) (TARPEYO / Nefecon)ApprovedSmall moleculeGlucocorticoid receptor
Canagliflozin (Invokana)ApprovedSmall moleculeSGLT2
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Daprodustat (Jesduvroq)ApprovedSmall moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
Difelikefalin (Korsuva)ApprovedPeptideKappa-opioid receptor (agonist, peripherally restricted)
Empagliflozin (Jardiance)ApprovedSmall moleculeSGLT2
Etelcalcetide (Parsabiv)ApprovedPeptideCalcium-sensing receptor (CaSR), allosteric agonist on parathyroid chief cells
Extended-Release Calcifediol (Rayaldee)ApprovedSmall moleculeVitamin D receptor (VDR), via conversion to calcitriol

…and 49 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2 (1)
Early phase / not applicable (6)
Appears in other studies (1)