Asset profile

Omega-3-acid ethyl esters (Lovaza)

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe... (FDA)

This approval is for an indication outside this terminal's covered markets; the covered program shown here is investigational. Regulatory approval supersedes design-level evidence grading for the approved use.

track record: Partial signal

Source for the program status

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 18 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Omega-3-Acid Ethyl Esters (Lovaza): this drugPhase 3Small moleculeTriglyceride metabolism
Alirocumab (Praluent)ApprovedMonoclonal antibodyPCSK9
Bempedoic Acid (Nexletol)ApprovedSmall moleculeAdenosine Triphosphate-Citrate Lyase Inhibitor, ATP citrate lyase
Bempedoic Acid / EzetimibeApprovedSmall moleculeATP citrate lyase (ACLY, bempedoic acid) and NPC1L1 (ezetimibe)
Cangrelor (Kengreal)ApprovedSmall moleculeP2Y12 receptor
Colchicine (cardiovascular) (Lodoco)ApprovedSmall moleculeMicrotubule/inflammasome (tubulin)
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Dulaglutide (Trulicity)ApprovedPeptideGLP-1 receptor
Evolocumab (Repatha)ApprovedMonoclonal antibodyPCSK9
Icosapent Ethyl (Vascepa)ApprovedSmall moleculeOmega-3 fatty acid (EPA)
Inclisiran (Leqvio)ApprovedRNA / oligonucleotidePCSK9
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Lomitapide (Juxtapid)ApprovedSmall moleculeMTP
NexlizetApproved——
Olezarsen (Tryngolza)ApprovedRNA / oligonucleotideAPOC3
Orforglipron (Foundayo)ApprovedSmall moleculeGLP-1 receptor

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
January 2027 (1)
Phase 2Breast Atypical Hyperplasia, Breast Carcinoma, Breast Ductal Carcinoma In Situ, Breast Lobular Carcinoma In SituRecruiting
Est. primary completion 2027-01-01 · NCT06195306 · CT.gov ↗
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2028 (1)
November 2028 (1)
Early phase / not applicableHealthyActive not recruiting
Est. primary completion 2028-11 · NCT00682318 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (23)
Phase 2/3 (3)
Phase 2 (21)
Phase 1/2 (15)
Phase 1 (9)
Phase 4 (31)
Early phase / not applicable (27)
Used as active comparator (4)
Appears in other studies (21)