Asset profile

KL-A167

Monoclonal antibody

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Ungradedevidence

Evidence outlook

Completed readouts not yet graded

This drug has completed mid- or late-stage studies whose evidence has not yet been graded on this platform. Where a sponsor has not posted registry results, topline data typically arrives via company announcements; see News.

Also in development:Non-Small Cell Lung Cancer · Phase 2

Featured evidence outside covered markets:NCT05294172 · Nasopharyngeal Carcinoma · Phase 3 · ungraded

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Competitive landscape

126 competitors in this universe: 10 direct rivals (same mechanism and indication), 1 same-class, 115 same-indication; 82 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
KL-A167: this drugPhase 3Monoclonal antibodyPD-L1
AtezolizumabApprovedMonoclonal antibodyPD-L1
DurvalumabApprovedMonoclonal antibodyPD-L1
Tecentriq Hybreza (atezolizumab And Hyaluronidase-Tqjs)ApprovedMonoclonal antibodyPD-L1
AdebrelimabPhase 3Monoclonal antibodyPD-L1
CS1001 Monoclonal AntibodyPhase 3Monoclonal antibodyPD-L1
EnvafolimabPhase 3Monoclonal antibodyPD-L1
PF-08046054Phase 3Antibody–drug conjugatePD-L1
HLX43Phase 2/3Antibody–drug conjugatePD-L1
177Lu-RAD204Phase 1RadiopharmaceuticalPD-L1
BPI-371153Phase 1Small moleculePD-L1
IBC-Ab002Phase 1Monoclonal antibodyPD-L1
Abemaciclib (Verzenio)ApprovedSmall moleculeCDK4 and CDK6
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alpelisib (BYL719)ApprovedSmall moleculePI3K-alpha

…and 111 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(10 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
December 2026 (2)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2026-12-30 · NCT07108816 · CT.gov ↗
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Phase 2Resectable Head and Neck Squamous Cell CarcinomaRecruiting
Est. primary completion 2026-12-31 · NCT07492914 · CT.gov ↗
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2027 (3)
June 2027 (1)
Phase 2Prostate Cancer (Adenocarcinoma), Prostate Cancer Metastatic Castration-Resistant …Recruiting
Est. primary completion 2027-06-30 · NCT07179783 · CT.gov ↗
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July 2027 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2027-07-30 · NCT07258108 · CT.gov ↗
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December 2027 (1)
Phase 3Nasopharyngeal Carcinoma, Recurrent or MetastaticActive not recruiting
Est. primary completion 2027-12 · NCT05294172 · CT.gov ↗
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2028 (5)
January 2028 (1)
Phase 2HR+/HER2- Metastatic Breast CancerNot yet recruiting
Est. primary completion 2028-01 · NCT07109284 · CT.gov ↗
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August 2028 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2028-08 · NCT07371208 · CT.gov ↗
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September 2028 (2)
Phase 2ESCC, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Esophageal Squamous Cell Carcinoma (ESCC), GC/GEJCNot yet recruiting
Est. primary completion 2028-09-01 · NCT07701681 · CT.gov ↗
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Phase 2Recurrent or Metastatic MSI-H/dMMR Gynecological MalignanciesNot yet recruiting
Est. primary completion 2028-09-01 · NCT07738757 · CT.gov ↗
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December 2028 (1)
Phase 2Small Cell Lung CancerRecruiting
Est. primary completion 2028-12-31 · NCT07296809 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2 (14)
Phase 1 (1)