Asset profile

ICA07

Cell therapy

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Earlyevidence

Evidence outlook

Early-stage evidence only

Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 60 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
ICA07: this drugPhase 1Cell therapyDopamine progenitor cells
Amantadine ER (Gocovri / ADS-5102)ApprovedSmall moleculeNMDA receptor
Apomorphine (Apokyn)ApprovedSmall moleculedopamine
Apomorphine Sublingual Film (Kynmobi)ApprovedSmall moleculedopamine
Crexont (IPX203)ApprovedSmall moleculedopamine precursor
Entacapone (Comtess)ApprovedSmall moleculeCOMT
Foslevodopa / Foscarbidopa (Vyalev)ApprovedSmall moleculedopamine precursor
Inbrija (CVT-301)ApprovedSmall moleculedopamine precursor
Istradefylline (Nourianz)ApprovedSmall moleculeadenosine A2A
Levodopa-Carbidopa Intestinal Gel (Duopa)ApprovedSmall moleculedopamine precursor
Opicapone (Ongentys)ApprovedSmall moleculeCOMT, PDE4
ParcopaApprovedSmall moleculedopamine precursor
Pimavanserin (Nuplazid)ApprovedSmall molecule5-HT2A/2C receptor, Serotonin 5-HT2A receptor (antagonist / inverse agonist)
Pramipexole (Sifrol/Mirapex)ApprovedSmall moleculeDopamine D2/D3 receptors
Pramipexole ER (Mirapex ER)ApprovedSmall moleculeDopamine D2 / D3 receptors
Rasagiline (Azilect)ApprovedSmall moleculeMAO-B

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.