Asset profile

Haloperidol

Small molecule

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Haloperidol: this drugApprovedSmall moleculeDopamine D2 receptor (antagonist)
Aripiprazole (Abilify Maintena)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT1A receptors (partial agonist), Dopamine D2/D3 and serotonin 5-HT1A receptor, Dopamine D2 receptor (partial agonist)
Aripiprazole (Abilify MyCite)ApprovedCombinationDopamine D2 and serotonin 5-HT1A receptors (partial agonist); serotonin 5-HT2A receptor (antagonist)
Aripiprazole (Abilify)ApprovedSmall moleculeDopamine D2/D3 and serotonin 5-HT1A receptor
Aripiprazole Lauroxil (Aristada Initio)ApprovedSmall moleculeDopamine D2/D3 and serotonin 5-HT1A receptor
Aripiprazole Lauroxil (Aristada)ApprovedSmall moleculeDopamine D2/D3 and serotonin 5-HT1A receptor
AsenapineApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Brexpiprazole (Rexulti)ApprovedSmall moleculeDopamine D2/D3 and serotonin 5-HT1A receptor
Cariprazine (Vraylar)ApprovedSmall moleculeDopamine D3/D2 receptor (partial agonist)
ClozapineApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Dexmedetomidine (Igalmi)Approved——
Dexmedetomidine (Igalmi)ApprovedSmall moleculeAlpha-2 adrenergic receptor (agonist)
FazacloApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Iloperidone (PD Psychosis Use) (Fanapt)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Loxapine (Adasuve)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Lumateperone (Caplyta)ApprovedSmall moleculeSerotonin 5-HT2A / dopamine D1-D2 receptor

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(6 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
October 2026 (1)
Phase 3Cannabinoid Hyperemesis SyndromeRecruiting
Est. primary completion 2026-10-31 · NCT07246187 · CT.gov ↗
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2027 (2)
February 2027 (1)
Phase 2/3Delirium, Epileptics, NeurolepticsRecruiting
Est. primary completion 2027-02-02 · NCT05431595 · CT.gov ↗
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December 2027 (1)
Phase 2Glioblastoma MultiformeNot yet recruiting
Est. primary completion 2027-12-31 · NCT06218524 · CT.gov ↗
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2028 (3)
January 2028 (1)
Phase 1Cannabinoid Hyperemesis SyndromeNot yet recruiting
Est. primary completion 2028-01 · NCT07726069 · CT.gov ↗
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August 2028 (1)
Phase 4Brain Insulin Sensitivity, Healthy Controls, CognitionRecruiting
Est. primary completion 2028-08 · NCT07109245 · CT.gov ↗
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December 2028 (1)
Phase 2/3Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant NeoplasmActive not recruiting
Est. primary completion 2028-12-31 · NCT03743649 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (18)
Phase 2/3 (5)
Phase 2 (10)
Phase 1 (10)
Phase 4 (34)
Early phase / not applicable (16)
Used as active comparator (38)
Appears in other studies (12)