Asset profile

Risperidone (Risperdal Consta)

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Schizophrenia

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Competitive landscape

67 competitors in this universe: 26 direct rivals (same mechanism and indication), 0 same-class, 41 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Risperidone (Risperdal Consta): this drugApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
AsenapineApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
ClozapineApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
FazacloApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Iloperidone (PD Psychosis Use) (Fanapt)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Loxapine (Adasuve)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
LurasidoneApprovedSmall moleculeDopamine D2/D3 receptor + 5-HT7 receptor, Dopamine D2 and serotonin 5-HT2A receptors (antagonist)
Milsaperidone (VHX-896)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Olanzapine (Zyprexa Relprevv)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Olanzapine (Zyprexa)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Paliperidone (Invega)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Paliperidone Palmitate (Erzofri)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Paliperidone Palmitate (Invega Hafyera)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Paliperidone Palmitate (Invega Sustenna)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
Paliperidone Palmitate (Invega Trinza)ApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)
PerserisApprovedSmall moleculeDopamine D2 and serotonin 5-HT2A receptors (antagonist)

…and 52 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

20 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
December 2027 (1)
Phase 4SchizophreniaActive not recruiting
Est. primary completion 2027-12-20 · NCT07047651 · CT.gov ↗
What to watch
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2032 (1)
February 2032 (1)
Phase 2SchizophreniaNot yet recruiting
Est. primary completion 2032-02-01 · NCT07152184 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (27)
Phase 2 (5)
Phase 1/2 (2)
Phase 1 (2)
Phase 4 (32)
Early phase / not applicable (7)
Used as active comparator (13)
Appears in other studies (2)