Asset profile

DWJ1276

Small molecule

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Dormantno recent development

Evidence outlook

No registered development activity since 2013

Registered studies concluded by 2013, with no approval on record and no active or planned study on the registry since. No sponsor statement of discontinuation has been sourced, but the trial history should be read as archival rather than an active program.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 8 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
DWJ1276: this drugPhase 3Small moleculeAngiotensin II receptor / HMG-CoA reductase
Aprocitentan (Tryvio)ApprovedSmall moleculeEndothelin receptor (ETA/ETB, dual)
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)
Bosentan (Tracleer)ApprovedSmall moleculeEndothelin receptor (ETA/ETB, dual)
Epoprostenol (Flolan)ApprovedSmall moleculeIP receptor (prostacyclin pathway)
Nitric Oxide (INOmax)ApprovedGas (inhaled)Nitric oxide
Sacubitril / Valsartan (Entresto)ApprovedSmall moleculeNeprilysin + Angiotensin II receptor (dual)
Treprostinil (Orenitram / Remodulin / Tyvaso)ApprovedSmall moleculeIP receptor (prostacyclin pathway)
Treprostinil (Yutrepia, Liquidia)ApprovedSmall moleculeIP receptor (prostacyclin pathway)
AD-209Phase 3Small moleculeAngiotensin II type 1 receptor / L-type calcium channel / Na-Cl cotransporter
AGSAVIPhase 3Small moleculeAngiotensin II receptor / Calcium channel / Thiazide-like diuretic
AJU-C52Phase 3Small moleculeAngiotensin II receptor / Calcium channel / Thiazide-like diuretic
Ambrisentan (Letairis)Phase 3Small moleculeEndothelin A receptor
C2402Phase 3Small molecule—
CJ-30060Phase 3Small moleculeAngiotensin II receptor / Calcium channel / HMG-CoA reductase
CJ-30061Phase 3Small moleculeAngiotensin II receptor / Calcium channel / HMG-CoA reductase

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 1 (1)
Appears in other studies (1)