Asset profile

D-2570

Small molecule

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

72 competitors in this universe: 1 direct rival (same mechanism and indication), 11 same-class, 60 same-indication; 54 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
D-2570: this drugPhase 3Small moleculeTYK2
TQH3906Phase 3Small moleculeTYK2
Deucravacitinib (Sotyktu)ApprovedSmall moleculeTYK2
EnvudeucitinibPhase 3Small moleculeTYK2
HS-10374Phase 3Small moleculeTYK2
ICP-488Phase 3Small moleculeTYK2
SYHX1901Phase 3Small moleculeTYK2
WD-890Phase 3Small moleculeTYK2
ZasocitinibPhase 3Small moleculeTYK2
CMS-D001Phase 2/3Small moleculeTYK2
BMS-986322Phase 2Small moleculeTYK2
GLPG3667Phase 2Small moleculeTYK2
CS32582Phase 1/2Small moleculeTYK2
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha
Adalimumab-Aaty (Yuflyma)Approved—TNF-alpha

…and 57 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
October 2026 (1)
Phase 1Healthy Adult Participants, Hepatic Impairment (HI)Recruiting
Est. primary completion 2026-10-31 · NCT07715149 · CT.gov ↗
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November 2026 (1)
Phase 1Renal ImpairmentNot yet recruiting
Est. primary completion 2026-11-21 · NCT07715175 · CT.gov ↗
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2027 (5)
July 2027 (2)
Phase 3Plaque PsoriasisRecruiting
Est. primary completion 2027-07-12 · NCT07326813 · CT.gov ↗
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Phase 3Plaque PsoriasisRecruiting
Est. primary completion 2027-07-28 · NCT07130604 · CT.gov ↗
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August 2027 (2)
Phase 2PsoriasisRecruiting
Est. primary completion 2027-08 · NCT07489885 · CT.gov ↗
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Phase 2PsA (Psoriatic Arthritis)Recruiting
Est. primary completion 2027-08-15 · NCT07315061 · CT.gov ↗
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November 2027 (1)
Phase 2Vitiligo, Non-Segmental Vitiligo (NSV)Recruiting
Est. primary completion 2027-11 · NCT07625891 · CT.gov ↗
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2028 (1)
August 2028 (1)
Phase 2Active Systemic Lupus ErythematosusRecruiting
Est. primary completion 2028-08-31 · NCT07311200 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (6)
Phase 1 (5)