Asset profile
CTX112
Biologic (subtype unspecified)
Evidence outlook
Early-stage evidence only
Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.
Also in development:Systemic Lupus Erythematosus · Phase 1Diffuse Large B-Cell Lymphoma
How the evidence outlook works ↗
Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
58 competitors in this universe: 8 direct rivals (same mechanism and indication), 2 same-class, 48 same-indication; 31 further along in development.
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| CTX112: this drug | Phase 1/2 | Biologic (subtype unspecified) | CD19 | ||
| Inebilizumab | Phase 3 | Monoclonal antibody | CD19 | ||
| FT819 | Phase 2 | Cell therapy | CD19 | ||
| Beijing Biotech Anti-CD19 CAR-T | Phase 1/2 | Cell therapy | CD19 | ||
| ABBV-319 | Phase 1 | — | CD19 | ||
| ABBV-519 | Phase 1 | — | CD19 | ||
| IC19 CAR-T | Phase 1 | Cell therapy | CD19 | ||
| UTAA09 | Phase 1 | Cell therapy | CD19 | ||
| ZM001 | Phase 1 | — | CD19 | ||
| Azercabtagene Zapreleucel (azer-Cel) | Phase 1 | Cell therapy | CD19 | ||
| CB-010 | Phase 1 | Cell therapy | CD19 | ||
| Anifrolumab | Approved | Monoclonal antibody | Type I interferon receptor, Type I interferon receptor subunit 1 (IFNAR1) | ||
| Avacopan (Tavneos) | Approved | Small molecule | Complement C5a receptor 1 (C5aR1/CD88) | ||
| Belimumab (GSK1550188) | Approved | Monoclonal antibody | BAFF / BLyS (B-lymphocyte stimulator), BAFF (BLyS) | ||
| Deucravacitinib (Sotyktu) | Approved | Small molecule | TYK2 | ||
| Epcoritamab | Approved | Multispecific antibody | — |
…and 43 more. Research shows the complete landscape.
Unlock the full comparison
Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Compare head-to-head
Upcoming events
(4 total)
Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.
2029 (1)
December 2029 (1)
What to watch
2030 (1)
January 2030 (1)
What to watch
2031 (1)
December 2031 (1)
What to watch
2033 (1)
December 2033 (1)
What to watch
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.