Asset profile

Epcoritamab

Multispecific antibody

Approved / Phase 4Mechanism not established
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Approvedregulatory verdict

Evidence outlook

Approved: Diffuse Large B-Cell Lymphoma, Follicular Lymphoma

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

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Competitive landscape

2 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 2 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Epcoritamab: this drugApprovedMultispecific antibody—
TafasitamabApprovedMonoclonal antibody—
CTX112Phase 1/2Biologic (subtype unspecified)CD19
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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(49 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
November 2026 (1)
Phase 2DLBCL - Diffuse Large B Cell Lymphoma, High-grade B-cell Lymphoma, High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements …Recruiting
Est. primary completion 2026-11 · NCT06287398 · CT.gov ↗
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December 2026 (1)
Phase 1Diffuse Large B-Cell LymphomaRecruiting
Est. primary completion 2026-12-31 · NCT06672705 · CT.gov ↗
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2027 (15)
February 2027 (1)
Phase 2Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Polymorphic Post-Transplant Lymphoproliferative Disorder …Recruiting
Est. primary completion 2027-02-18 · NCT06723457 · CT.gov ↗
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March 2027 (1)
Phase 2Diffuse Large B-Cell LymphomaActive not recruiting
Est. primary completion 2027-03 · NCT05451810 · CT.gov ↗
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April 2027 (1)
Phase 2Waldenstrom Macroglobulinemia, B-Cell Lymphoproliferative DisorderRecruiting
Est. primary completion 2027-04-30 · NCT06510491 · CT.gov ↗
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June 2027 (1)
Phase 3Diffuse Large B-Cell LymphomaActive not recruiting
Est. primary completion 2027-06 · NCT05578976 · CT.gov ↗
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July 2027 (2)
Phase 1Leukemia, Chronic Lymphocytic, Richter SyndromeActive not recruiting
Est. primary completion 2027-07-01 · NCT06676033 · CT.gov ↗
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Phase 2CLL/SLL, CLL, SLL, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Small Lymphocytic Lymphoma Variant …Recruiting
Est. primary completion 2027-07-01 · NCT07108998 · CT.gov ↗
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August 2027 (2)
Phase 2Follicular LymphomaActive not recruiting
Est. primary completion 2027-08-10 · NCT06112847 · CT.gov ↗
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Phase 1/2Diffuse Large B-Cell LymphomaRecruiting
Est. primary completion 2027-08-31 · NCT06536049 · CT.gov ↗
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September 2027 (3)
Phase 1/2Follicular LymphomaActive not recruiting
Est. primary completion 2027-09 · NCT04542824 · CT.gov ↗
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Phase 2Relapsed/Refractory Diffuse Large B Cell LymphomaRecruiting
Est. primary completion 2027-09 · NCT07451652 · CT.gov ↗
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Phase 1/2Diffuse Large B-Cell LymphomaActive not recruiting
Est. primary completion 2027-09-30 · NCT04663347 · CT.gov ↗
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October 2027 (2)
Phase 2Diffuse Large B-Cell LymphomaRecruiting
Est. primary completion 2027-10 · NCT06458439 · CT.gov ↗
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Phase 1/2Relapsed/Refractory Non-Hodgkin LymphomaRecruiting
Est. primary completion 2027-10-28 · NCT06090539 · CT.gov ↗
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November 2027 (1)
Phase 2Large Cell Lymphoma, Diffuse, Relapsed Cancer, Refractory CancerRecruiting
Est. primary completion 2027-11-24 · NCT05852717 · CT.gov ↗
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December 2027 (1)
Phase 1/2Relapsed/Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Richter's Syndrome …Active not recruiting
Est. primary completion 2027-12 · NCT04623541 · CT.gov ↗
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2028 (13)
January 2028 (1)
Phase 2Primary CNS Lymphoma (PCNSL)Recruiting
Est. primary completion 2028-01 · NCT06931652 · CT.gov ↗
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February 2028 (1)
Phase 2Follicular LymphomaRecruiting
Est. primary completion 2028-02 · NCT05783609 · CT.gov ↗
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March 2028 (1)
Phase 3Diffuse Large B-Cell LymphomaActive not recruiting
Est. primary completion 2028-03 · NCT06508658 · CT.gov ↗
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July 2028 (3)
Phase 2Diffuse Large B-Cell LymphomaNot yet recruiting
Est. primary completion 2028-07 · NCT07814001 · CT.gov ↗
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Phase 2Diffuse Large B-Cell LymphomaRecruiting
Est. primary completion 2028-07-01 · NCT06905509 · CT.gov ↗
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Phase 2Large B-cell LymphomaRecruiting
Est. primary completion 2028-07-31 · NCT06045247 · CT.gov ↗
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August 2028 (2)
Phase 1Primary Central Nervous System Lymphoma (PCNSL), Primary Central Nervous System Lymphoma, Relapsed Primary Central Nervous System Lymphoma …Recruiting
Est. primary completion 2028-08 · NCT07082868 · CT.gov ↗
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Phase 2Diffuse Large B-Cell LymphomaNot yet recruiting
Est. primary completion 2028-08-31 · NCT07588698 · CT.gov ↗
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September 2028 (1)
Phase 1Non-Hodgkin Lymphoma, Cytokine Release SyndromeRecruiting
Est. primary completion 2028-09-01 · NCT06447376 · CT.gov ↗
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October 2028 (2)
Phase 2CLL, CLL (Chronic Lymphocytic Leukemia), Chronic Lymphocytic Leukemia (CLL), BTKiNot yet recruiting
Est. primary completion 2028-10 · NCT07819214 · CT.gov ↗
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Phase 2Marginal Zone Lymphoma, Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue, Splenic Marginal Zone Lymphoma …Recruiting
Est. primary completion 2028-10-15 · NCT06796998 · CT.gov ↗
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November 2028 (1)
Phase 1Non-hodgkin LymphomaActive not recruiting
Est. primary completion 2028-11 · NCT05206357 · CT.gov ↗
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December 2028 (1)
Phase 2Follicular LymphomaNot yet recruiting
Est. primary completion 2028-12-31 · NCT07783594 · CT.gov ↗
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2029 (8)
January 2029 (1)
Phase 1/2DLBCL, High-grade B-cell Lymphoma (HGBCL), Primary Mediastinal Large B-cell Lymphoma (PMBCL), FL, MCL, Small Lymphocytic Lymphoma (SLL) …Active not recruiting
Est. primary completion 2029-01 · NCT03625037 · CT.gov ↗
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March 2029 (1)
Phase 1/2CLL/SLLRecruiting
Est. primary completion 2029-03 · NCT05791409 · CT.gov ↗
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May 2029 (1)
Phase 2Follicular LymphomaRecruiting
Est. primary completion 2029-05-31 · NCT05848765 · CT.gov ↗
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June 2029 (1)
Phase 2Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaRecruiting
Est. primary completion 2029-06-08 · NCT07218510 · CT.gov ↗
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October 2029 (1)
Phase 2Diffuse Large B-Cell LymphomaRecruiting
Est. primary completion 2029-10-15 · NCT07365306 · CT.gov ↗
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December 2029 (3)
Phase 3Follicular LymphomaActive not recruiting
Est. primary completion 2029-12 · NCT05409066 · CT.gov ↗
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Phase 2Diffuse Large B-Cell LymphomaRecruiting
Est. primary completion 2029-12-31 · NCT06238648 · CT.gov ↗
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Phase 2Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaNot yet recruiting
Est. primary completion 2029-12-31 · NCT07738887 · CT.gov ↗
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2030 (5)
March 2030 (1)
Phase 2Follicular LymphomaRecruiting
Est. primary completion 2030-03-01 · NCT06563596 · CT.gov ↗
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April 2030 (1)
Phase 2Diffuse Large B-Cell LymphomaRecruiting
Est. primary completion 2030-04-30 · NCT07197307 · CT.gov ↗
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May 2030 (1)
Phase 2Diffuse Large B-Cell LymphomaRecruiting
Est. primary completion 2030-05-31 · NCT07097363 · CT.gov ↗
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June 2030 (1)
Phase 1Diffuse Large B Cell LymphomaRecruiting
Est. primary completion 2030-06 · NCT07528352 · CT.gov ↗
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October 2030 (1)
Phase 1Diffuse Large B-Cell LymphomaNot yet recruiting
Est. primary completion 2030-10-08 · NCT07714421 · CT.gov ↗
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2031 (4)
January 2031 (1)
Phase 2Large B-cell Lymphoma, RelapseRecruiting
Est. primary completion 2031-01-07 · NCT06919939 · CT.gov ↗
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May 2031 (1)
Phase 2Adult Burkitt LymphomaNot yet recruiting
Est. primary completion 2031-05-30 · NCT07662928 · CT.gov ↗
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September 2031 (1)
Phase 1/2Recurrent B-Cell Non-Hodgkin Lymphoma, Refractory B-cell Non-Hodgkin LymphomaRecruiting
Est. primary completion 2031-09-30 · NCT07283679 · CT.gov ↗
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December 2031 (1)
Phase 2Large B Cell LymphomaRecruiting
Est. primary completion 2031-12-27 · NCT07126236 · CT.gov ↗
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2032 (1)
November 2032 (1)
Phase 2Non-Hodgkin LymphomaActive not recruiting
Est. primary completion 2032-11 · NCT05283720 · CT.gov ↗
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2037 (1)
November 2037 (1)
Phase 3Follicular LymphomaActive not recruiting
Est. primary completion 2037-11 · NCT06191744 · CT.gov ↗
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (6)
Phase 2 (36)
Phase 1/2 (10)
Phase 1 (7)