Asset profile
CT-P10
Monoclonal antibody
Evidence outlook · lead readout
NCT02149121 · Rheumatoid Arthritis
The completed lead evidence has the design features that historically survive confirmatory trials: randomized, controlled, and adequately powered against a prespecified clinically accepted endpoint.
NCT02149121: This was a randomized, quadruple-blind, active-controlled trial with an adequately sized population (384 enrolled) that pre-specified formal equivalence margins for both its pharmacokinetic and its clinical disease-activity (DAS28-CRP) primary endpoints, and every comparison landed entirely within the required margin, meaning the biosimilar demonstrated therapeutic equivalence to the reference product on a validated hard clinical measure of rheumatoid arthritis activity, not just a proxy lab value.
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Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
70 competitors in this universe: 5 direct rivals (same mechanism and indication), 10 same-class, 55 same-indication; 29 further along in development.
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| CT-P10: this drug | Phase 3 | Monoclonal antibody | CD20 | ||
| PF-05280586 | Approved | Biologic (subtype unspecified) | CD20 | ||
| Rituximab | Approved | Monoclonal antibody | CD20, CD20-directed Cytolytic Antibody | ||
| Acellbia | Phase 3 | Monoclonal antibody | CD20 | ||
| HLX01 | Phase 3 | Monoclonal antibody | CD20 | ||
| SAR448501 | Phase 1 | Multispecific antibody | CD20 | ||
| Ocrelizumab | Approved | Monoclonal antibody | CD20 | ||
| Ocrevus Zunovo | Approved | Monoclonal antibody | CD20 | ||
| Ofatumumab | Approved | Monoclonal antibody | CD20 | ||
| Ublituximab | Approved | Monoclonal antibody | CD20 | ||
| ABP 692 | Phase 3 | Monoclonal antibody | CD20 | ||
| BCD-132 | Phase 3 | Monoclonal antibody | CD20 | ||
| BCD-281 | Phase 3 | Monoclonal antibody | CD20 | ||
| CT-P53 | Phase 3 | Monoclonal antibody | CD20 | ||
| Divozilimab | Phase 3 | Monoclonal antibody | CD20 | ||
| MIL62 | Phase 3 | Monoclonal antibody | CD20 |
…and 55 more. Research shows the complete landscape.
Unlock the full comparison
Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Upcoming events
No upcoming readouts on record for this asset.
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.