Asset profile

CM336

Multispecific antibody

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Phase 3underway

Evidence outlook · registrational

Multiple Myeloma: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2027-09.

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Competitive landscape

71 competitors in this universe: 10 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication; 23 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
CM336: this drugPhase 3Multispecific antibodyBCMA x CD3
ElranatamabApprovedMultispecific antibodyBCMA x CD3
LinvoseltamabApprovedMultispecific antibodyBCMA x CD3
TeclistamabApprovedMultispecific antibodyBCMA x CD3
BCD-248Phase 3Multispecific antibodyBCMA x CD3
EtentamigPhase 3Multispecific antibodyBCMA x CD3
F182112Phase 3Multispecific antibodyBCMA x CD3
GR1803Phase 3Multispecific antibodyBCMA x CD3
TQB2934Phase 3Multispecific antibodyBCMA x CD3
YKST02Phase 2Multispecific antibodyBCMA x CD3
REGN5459Phase 1/2Multispecific antibodyBCMA x CD3
CizutamigPhase 1Multispecific antibodyBCMA x CD3
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA

…and 56 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(14 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (3)
December 2026 (3)
Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2026-12 · NCT05299424 · CT.gov ↗
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Phase 2Solitary Bone Plasmacytoma, Plasmacytoma of Bone, Plasma Cell DisordersRecruiting
Est. primary completion 2026-12-01 · NCT07115667 · CT.gov ↗
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Phase 2POEMS SyndromeRecruiting
Est. primary completion 2026-12-01 · NCT07115654 · CT.gov ↗
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2027 (7)
January 2027 (1)
Phase 2Autoimmune Bullous DiseaseRecruiting
Est. primary completion 2027-01-01 · NCT06900010 · CT.gov ↗
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May 2027 (1)
Phase 1Multiple MyelomaNot yet recruiting
Est. primary completion 2027-05-31 · NCT07407010 · CT.gov ↗
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July 2027 (1)
Phase 2Multiple MyelomaNot yet recruiting
Est. primary completion 2027-07-09 · NCT07648459 · CT.gov ↗
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August 2027 (2)
Phase 1/2Multiple MyelomaNot yet recruiting
Est. primary completion 2027-08-01 · NCT07687004 · CT.gov ↗
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Early phase / not applicableMultiple MyelomaRecruiting
Est. primary completion 2027-08-01 · NCT06745687 · CT.gov ↗
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September 2027 (1)
Phase 3Multiple MyelomaNot yet recruiting
Est. primary completion 2027-09 · NCT07181239 · CT.gov ↗
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November 2027 (1)
Phase 1/2Autoimmune Cytopenia, Immune Thrombocytopenia (ITP), Autoimmune Hemolytic Anemia, Evans SyndromeRecruiting
Est. primary completion 2027-11-18 · NCT07175493 · CT.gov ↗
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2028 (2)
April 2028 (1)
Phase 1Primary Sjögren's Syndrome (pSS)Not yet recruiting
Est. primary completion 2028-04 · NCT07642843 · CT.gov ↗
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May 2028 (1)
Phase 2Multiple MyelomaRecruiting
Est. primary completion 2028-05-01 · NCT07585760 · CT.gov ↗
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2029 (2)
April 2029 (1)
Phase 2Multiple MyelomaNot yet recruiting
Est. primary completion 2029-04-15 · NCT07830485 · CT.gov ↗
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June 2029 (1)
Phase 2Plasma Cell Leukemia (PCL)Recruiting
Est. primary completion 2029-06-30 · NCT07652905 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2 (9)
Phase 1/2 (3)
Phase 1 (2)
Early phase / not applicable (1)