Head-to-head evidence

CM336 vs Teclistamab

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Multiple Myeloma

Shared mechanism: BCMA x CD3 · full Multiple Myeloma pipeline

CM336

Developed by Keymed Biosciences

Phase 3 in Multiple Myelomabispecific antibody
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: December 2026 · NCT05299424 (registry estimate)

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Teclistamab

Marketed by Johnson & Johnson

Approved in Multiple Myelomabispecific antibody (T-cell engager)
Weak signal

NCT04696809 · Phase 1/2 · completed

The study is a single-group, open-label trial without randomization or a comparator arm, so responses cannot be directly compared with another treatment. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

Phase 2 portion's primary endpoint is overall response rate (shown); interim data cutoff April 2024, before study completion. Single-arm, no comparator.

Next expected readout: November 2026 · NCT06505369 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: CM336's landscape · Teclistamab's landscape