Asset profile

Alisertib

Small molecule

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Ungradedevidence

Evidence outlook

Completed readouts not yet graded

This drug has completed mid- or late-stage studies whose evidence has not yet been graded on this platform. Where a sponsor has not posted registry results, topline data typically arrives via company announcements; see News.

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Competitive landscape

2 competitors in this universe: 0 direct rivals (same mechanism and indication), 1 same-class, 1 same-indication; 1 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Alisertib: this drugPhase 3Small moleculeAurora kinase A (AURKA)
VIC-1911Phase 1/2Small moleculeAurora kinase A (AURKA)
LurbinectedinApprovedSmall moleculeAlkylating Drug
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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
October 2027 (1)
Phase 2Small Cell Lung CancerRecruiting
Est. primary completion 2027-10-30 · NCT06095505 · CT.gov ↗
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December 2027 (1)
Phase 2Hormone Receptor Positive HER-2 Negative Breast Cancer, Metastatic Breast Cancer, Recurrent Breast CancerRecruiting
Est. primary completion 2027-12-30 · NCT06369285 · CT.gov ↗
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2028 (2)
March 2028 (1)
Phase 2Small Cell Lung CancerRecruiting
Est. primary completion 2028-03-31 · NCT07465757 · CT.gov ↗
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September 2028 (1)
Phase 2HR+/HER2+ Breast Cancer, Metastatic Breast CancerNot yet recruiting
Est. primary completion 2028-09 · NCT07706179 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2 (22)
Phase 1/2 (7)
Phase 1 (34)
Early phase / not applicable (1)