Asset profile

XmAb541

Multispecific antibody

Phase 1Mechanism not established
Preview Research free. Sign in to unlock 3 full asset or company pages every day, no card needed.Sign in to unlock this page
Earlyevidence

Evidence outlook

Early-stage evidence only

Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

How the evidence outlook works ↗

Competitive landscape

12 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 12 same-indication; 10 further along in development.

Unlock with Research ↗
DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
XmAb541: this drugPhase 1Multispecific antibody—
AvutometinibApprovedSmall moleculeRAF/MEK, MEK1/2 and RAF (CRAF, BRAF)
DefactinibApprovedSmall moleculeFAK
NiraparibApprovedSmall moleculePARP1/2
Relacorilant (Lifyorli)ApprovedSmall moleculeGlucocorticoid receptor
INCB123667Phase 3Small molecule—
Olvimulogene NanivacirepvecPhase 3Oncolytic VirusNo discrete molecular target
Rina-SPhase 3Small moleculeFolate receptor alpha (FRα)
Luveltamab TazevibulinPhase 2/3Antibody–drug conjugate—
BirinapantPhase 2——
StenoparibPhase 2Small molecule—
COM701Phase 1Small molecule—
IDE-161Phase 1Small moleculePARG
Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
December 2027 (1)
Phase 1Ovarian CancerRecruiting
Est. primary completion 2027-12 · NCT06276491 · CT.gov ↗
What to watch
Unlock with Research ↗
2028 (1)
December 2028 (1)
Phase 1Ovarian CancerRecruiting
Est. primary completion 2028-12 · NCT07593092 · CT.gov ↗
What to watch
Unlock with Research ↗

See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.