Asset profile
TY-9591
Small molecule
Evidence outlook · registrational
Non-Small Cell Lung Cancer: registrational readout pending
Entered Phase 3 on weak signal mid-stage evidence. The registry's posted readout date (2025-05) has passed without a status update. Check News for topline announcements.
NCT05146219: The study treated 29 participants in a single arm without randomization, blinding, or a control group. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.
How the evidence outlook works ↗
Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
102 competitors in this universe: 41 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication; 58 further along in development.
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| TY-9591: this drug | Phase 3 | Small molecule | EGFR | ||
| Gefitinib | Approved | Small molecule | EGFR | ||
| Lazertinib | Approved | Small molecule | EGFR | ||
| Osimertinib (Tagrisso) | Approved | Small molecule | EGFR | ||
| Sunvozertinib | Approved | Small molecule | EGFR | ||
| Alflutinib | Phase 3 | Small molecule | EGFR | ||
| Almonertinib | Phase 3 | Small molecule | EGFR | ||
| Befotertinib | Phase 3 | Small molecule | EGFR | ||
| BPI-7711 | Phase 3 | Small molecule | EGFR | ||
| CPO301 | Phase 3 | Antibody–drug conjugate | EGFR | ||
| FHND9041 | Phase 3 | Small molecule | EGFR | ||
| Icotinib | Phase 3 | Small molecule | EGFR | ||
| JMT101 | Phase 3 | Monoclonal antibody | EGFR | ||
| Limertinib | Phase 3 | Small molecule | EGFR, EGFR T790M (resistant mutant, selective over wild-type EGFR) | ||
| PLB1004 | Phase 3 | Small molecule | EGFR | ||
| SH-1028 | Phase 3 | Small molecule | EGFR |
…and 87 more. Research shows the complete landscape.
Unlock the full comparison
Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Compare head-to-head
35 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.
Upcoming events
(1 total)
Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.
2027 (1)
December 2027 (1)
What to watch
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.