Asset profile

IMVT-1402

Biologic (subtype unspecified)

Phase 3Mechanism not established
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Phase 3underway

Evidence outlook · registrational

Myasthenia Gravis: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2027-12.

Also in development:Rheumatoid Arthritis · Phase 2Graves' Disease · Phase 2Chronic Inflammatory Demyelinating Polyneuropathy · Phase 2Sjögren's DiseaseCutaneous Lupus Erythematosus · Phase 2

How the evidence outlook works ↗

Competitive landscape

63 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 63 same-indication; 25 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
IMVT-1402: this drugPhase 3Biologic (subtype unspecified)—
Abatacept (Orencia)ApprovedProtein / enzyme therapeuticCD80/CD86 (CTLA-4-Ig), Selective T Cell Costimulation Modulator, CD80/CD86 (B7-1/B7-2) on antigen-presenting cells
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Ryvk (Simlandi)Approved—TNF-alpha
Aldesleukin (Proleukin)ApprovedRecombinant Cytokine (il-2)Interleukin-2 receptor (IL-2R)
Anakinra (r-metHuIL-1ra)ApprovedProtein / enzyme therapeuticInterleukin-1 receptor (IL-1R), Interleukin-1 receptor type 1 (IL-1R1)
Baricitinib (Olumiant)ApprovedSmall moleculeJAK, JAK1/2
Certolizumab Pegol (Cimzia)ApprovedAntibody fragmentTNF-alpha
CT-P13 (Inflectra / Remsima)ApprovedMonoclonal antibodyTNF-alpha
CT-P47 (tocilizumab) (Avtozma)ApprovedMonoclonal antibodyIL-6R antagonist
DenosumabApprovedMonoclonal antibodyRANKL
Etanercept (Enbrel)ApprovedProtein / enzyme therapeuticTNF-alpha, TNF-alpha / TNF-beta (lymphotoxin-alpha)
Golimumab (Simponi)ApprovedMonoclonal antibodyTNF-alpha
HZT-501 (Duexis)ApprovedSmall moleculeCyclooxygenase (COX-1/COX-2) plus histamine H2 receptor
Infliximab (Remicade)ApprovedMonoclonal antibodyTNF-alpha

…and 48 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(7 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (3)
May 2027 (1)
Phase 2Graves' DiseaseRecruiting
Est. primary completion 2027-05 · NCT07018323 · CT.gov ↗
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September 2027 (1)
Phase 2Rheumatoid ArthritisActive not recruiting
Est. primary completion 2027-09 · NCT06754462 · CT.gov ↗
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December 2027 (1)
Phase 3Myasthenia GravisRecruiting
Est. primary completion 2027-12 · NCT07039916 · CT.gov ↗
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2028 (3)
June 2028 (1)
Phase 2Graves' DiseaseRecruiting
Est. primary completion 2028-06 · NCT06727604 · CT.gov ↗
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July 2028 (1)
Phase 2Primary Sjögren's SyndromeActive not recruiting
Est. primary completion 2028-07 · NCT06979531 · CT.gov ↗
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August 2028 (1)
Phase 2Chronic Inflammatory Demyelinating PolyneuropathyRecruiting
Est. primary completion 2028-08 · NCT07032662 · CT.gov ↗
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2030 (1)
March 2030 (1)
Phase 2Graves' DiseaseEnrolling by invitation
Est. primary completion 2030-03 · NCT07286006 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2 (7)